| Friday, January 1st, 2010 |
| Drafted CF M. Mantle in the 2010 inaugural draft (Round 1, Pick 7, 7th overall Pick). |
| Drafted C B. Delancey in the 2010 inaugural draft (Round 2, Pick 24, 54th overall Pick). |
| Drafted RF H. Baines in the 2010 inaugural draft (Round 3, Pick 7, 67th overall Pick). |
| Drafted SP E. Morris in the 2010 inaugural draft (Round 4, Pick 24, 114th overall Pick). |
| Drafted SP H. Krause in the 2010 inaugural draft (Round 5, Pick 7, 127th overall Pick). |
| Drafted 1B H. Killebrew in the 2010 inaugural draft (Round 6, Pick 24, 174th overall Pick). |
| Drafted SP S. Stratton in the 2010 inaugural draft (Round 7, Pick 7, 187th overall Pick). |
| Drafted 3B M. Williams in the 2010 inaugural draft (Round 8, Pick 24, 234th overall Pick). |
| Drafted CL W. Hernandez in the 2010 inaugural draft (Round 9, Pick 7, 247th overall Pick). |
| Drafted MR T. Niedenfuer in the 2010 inaugural draft (Round 10, Pick 24, 294th overall Pick). |
| Drafted CL R. Beck in the 2010 inaugural draft (Round 11, Pick 7, 307th overall Pick). |
| Drafted SP N. Maddox in the 2010 inaugural draft (Round 12, Pick 24, 354th overall Pick). |
| Drafted SP J. Taylor in the 2010 inaugural draft (Round 13, Pick 7, 367th overall Pick). |
| Drafted MR T. Hughson in the 2010 inaugural draft (Round 14, Pick 24, 414th overall Pick). |
| Drafted SS L. Boudreau in the 2010 inaugural draft (Round 15, Pick 7, 427th overall Pick). |
| Drafted 2B R. Hunt in the 2010 inaugural draft (Round 16, Pick 24, 474th overall Pick). |
| Drafted MR M. Rojas in the 2010 inaugural draft (Round 17, Pick 7, 487th overall Pick). |
| Drafted MR M. Davis in the 2010 inaugural draft (Round 18, Pick 24, 534th overall Pick). |
| Drafted C B. Freehan in the 2010 inaugural draft (Round 19, Pick 7, 547th overall Pick). |
| Drafted LF R. Monday in the 2010 inaugural draft (Round 20, Pick 24, 594th overall Pick). |
| Drafted LF S. Kemp in the 2010 inaugural draft (Round 21, Pick 7, 607th overall Pick). |
| Drafted LF C. Lee in the 2010 inaugural draft (Round 22, Pick 24, 654th overall Pick). |
| Drafted LF G. Gross in the 2010 inaugural draft (Round 23, Pick 7, 667th overall Pick). |
| Drafted 1B A. Thornton in the 2010 inaugural draft (Round 24, Pick 24, 714th overall Pick). |
| Drafted LF A. McHenry in the 2010 inaugural draft (Round 25, Pick 7, 727th overall Pick). |
| Drafted RF I. Boone in the 2010 inaugural draft (Round 26, Pick 24, 774th overall Pick). |
| Drafted CF B. Williams in the 2010 inaugural draft (Round 27, Pick 7, 787th overall Pick). |
| Drafted 3B G. Kell in the 2010 inaugural draft (Round 28, Pick 24, 834th overall Pick). |
| Drafted C E. Howard in the 2010 inaugural draft (Round 29, Pick 7, 847th overall Pick). |
| Drafted MR A. Reynolds in the 2010 inaugural draft (Round 30, Pick 24, 894th overall Pick). |
| Drafted 1B T. Martinez in the 2010 inaugural draft (Round 31, Pick 7, 907th overall Pick). |
| Drafted LF W. Horton in the 2010 inaugural draft (Round 32, Pick 24, 954th overall Pick). |
| Drafted MR S. Howe in the 2010 inaugural draft (Round 33, Pick 7, 967th overall Pick). |
| Drafted CL B. Apodaca in the 2010 inaugural draft (Round 34, Pick 24, 1014th overall Pick). |
| Drafted SS L. Lary in the 2010 inaugural draft (Round 35, Pick 7, 1027th overall Pick). |
| Drafted 2B C. Biggio in the 2010 inaugural draft (Round 36, Pick 24, 1074th overall Pick). |
| Drafted MR A. Nehf in the 2010 inaugural draft (Round 37, Pick 7, 1087th overall Pick). |
| Drafted MR M. Brown in the 2010 inaugural draft (Round 38, Pick 24, 1134th overall Pick). |
| Drafted 1B F. Alou in the 2010 inaugural draft (Round 39, Pick 7, 1147th overall Pick). |
| Drafted 1B B. Robinson in the 2010 inaugural draft (Round 40, Pick 24, 1194th overall Pick). |
| Drafted 3B G. Nettles in the 2010 inaugural draft (Round 41, Pick 7, 1207th overall Pick). |
