| Friday, January 1st, 2010 |
| Drafted LF B. Ruth in the 2010 inaugural draft (Round 1, Pick 10, 10th overall Pick). |
| Drafted 1B G. Sisler in the 2010 inaugural draft (Round 2, Pick 21, 51st overall Pick). |
| Drafted RF J. Canseco in the 2010 inaugural draft (Round 3, Pick 10, 70th overall Pick). |
| Drafted SP J. Pfiester in the 2010 inaugural draft (Round 4, Pick 21, 111st overall Pick). |
| Drafted SP M. Scott in the 2010 inaugural draft (Round 5, Pick 10, 130th overall Pick). |
| Drafted SS J. Sewell in the 2010 inaugural draft (Round 6, Pick 21, 171st overall Pick). |
| Drafted C J. Milligan in the 2010 inaugural draft (Round 7, Pick 10, 190th overall Pick). |
| Drafted SP A. Hrabosky in the 2010 inaugural draft (Round 8, Pick 21, 231st overall Pick). |
| Drafted MR J. Brewer in the 2010 inaugural draft (Round 9, Pick 10, 250th overall Pick). |
| Drafted 3B R. Santo in the 2010 inaugural draft (Round 10, Pick 21, 291st overall Pick). |
| Drafted 2B L. Doyle in the 2010 inaugural draft (Round 11, Pick 10, 310th overall Pick). |
| Drafted MR V. Gregg in the 2010 inaugural draft (Round 12, Pick 21, 351st overall Pick). |
| Drafted MR P. Perez in the 2010 inaugural draft (Round 13, Pick 10, 370th overall Pick). |
| Drafted CF M. Griffin in the 2010 inaugural draft (Round 14, Pick 21, 411st overall Pick). |
| Drafted SP G. Zettlein in the 2010 inaugural draft (Round 15, Pick 10, 430th overall Pick). |
| Drafted MR W. Twitchell in the 2010 inaugural draft (Round 16, Pick 21, 471st overall Pick). |
| Drafted MR B. Feller in the 2010 inaugural draft (Round 17, Pick 10, 490th overall Pick). |
| Drafted SP R. Jones in the 2010 inaugural draft (Round 18, Pick 21, 531st overall Pick). |
| Drafted C T. Simmons in the 2010 inaugural draft (Round 19, Pick 10, 550th overall Pick). |
| Drafted LF W. Covington in the 2010 inaugural draft (Round 20, Pick 21, 591st overall Pick). |
| Drafted DH R. Jefferson in the 2010 inaugural draft (Round 21, Pick 10, 610th overall Pick). |
| Drafted 3B J. Torre in the 2010 inaugural draft (Round 22, Pick 21, 651st overall Pick). |
| Drafted SP M. Stratton in the 2010 inaugural draft (Round 23, Pick 10, 670th overall Pick). |
| Drafted SP G. Winter in the 2010 inaugural draft (Round 24, Pick 21, 711st overall Pick). |
| Drafted SP L. Gomez in the 2010 inaugural draft (Round 25, Pick 10, 730th overall Pick). |
| Drafted SP S. Barber in the 2010 inaugural draft (Round 26, Pick 21, 771st overall Pick). |
| Drafted MR P. Richert in the 2010 inaugural draft (Round 27, Pick 10, 790th overall Pick). |
| Drafted LF R. Blades in the 2010 inaugural draft (Round 28, Pick 21, 831st overall Pick). |
| Drafted CF G. Harper in the 2010 inaugural draft (Round 29, Pick 10, 850th overall Pick). |
| Drafted 3B R. Ventura in the 2010 inaugural draft (Round 30, Pick 21, 891st overall Pick). |
| Drafted 1B J. Anderson in the 2010 inaugural draft (Round 31, Pick 10, 910th overall Pick). |
| Drafted 2B P. Lloyd in the 2010 inaugural draft (Round 32, Pick 21, 951st overall Pick). |
| Drafted SS J. Peters in the 2010 inaugural draft (Round 33, Pick 10, 970th overall Pick). |
| Drafted CL J. Montgomery in the 2010 inaugural draft (Round 34, Pick 21, 1011st overall Pick). |
| Drafted C A. Ashby in the 2010 inaugural draft (Round 35, Pick 10, 1030th overall Pick). |
| Drafted SP A. Ditmar in the 2010 inaugural draft (Round 36, Pick 21, 1071st overall Pick). |
| Drafted CL A. Adams in the 2010 inaugural draft (Round 37, Pick 10, 1090th overall Pick). |
| Drafted RF S. Seybold in the 2010 inaugural draft (Round 38, Pick 21, 1131st overall Pick). |
| Drafted LF C. Jamieson in the 2010 inaugural draft (Round 39, Pick 10, 1150th overall Pick). |
| Drafted RF H. Hooper in the 2010 inaugural draft (Round 40, Pick 21, 1191st overall Pick). |
| Drafted 2B G. Cutshaw in the 2010 inaugural draft (Round 41, Pick 10, 1210th overall Pick). |
