| Friday, January 1st, 2010 |
| Drafted C L. Santop in the 2010 inaugural draft (Round 1, Pick 2, 2nd overall Pick). |
| Drafted CF B. Higginson in the 2010 inaugural draft (Round 2, Pick 29, 59th overall Pick). |
| Drafted 1B N. Cash in the 2010 inaugural draft (Round 3, Pick 2, 62nd overall Pick). |
| Drafted SP J. Whitney in the 2010 inaugural draft (Round 4, Pick 29, 119th overall Pick). |
| Drafted SP J. McCormick in the 2010 inaugural draft (Round 5, Pick 2, 122nd overall Pick). |
| Drafted LF T. Davis in the 2010 inaugural draft (Round 6, Pick 29, 179th overall Pick). |
| Drafted MR B. Blyleven in the 2010 inaugural draft (Round 7, Pick 2, 182nd overall Pick). |
| Drafted SP S. Koufax in the 2010 inaugural draft (Round 8, Pick 29, 239th overall Pick). |
| Drafted 3B K. Caminiti in the 2010 inaugural draft (Round 9, Pick 2, 242nd overall Pick). |
| Drafted MR D. Ellsworth in the 2010 inaugural draft (Round 10, Pick 29, 299th overall Pick). |
| Drafted MR D. Murray in the 2010 inaugural draft (Round 11, Pick 2, 302nd overall Pick). |
| Drafted SS D. Bartell in the 2010 inaugural draft (Round 12, Pick 29, 359th overall Pick). |
| Drafted MR H. Vaughn in the 2010 inaugural draft (Round 13, Pick 2, 362nd overall Pick). |
| Drafted 2B K. Kelly in the 2010 inaugural draft (Round 14, Pick 29, 419th overall Pick). |
| Drafted SP P. Galvin in the 2010 inaugural draft (Round 15, Pick 2, 422nd overall Pick). |
| Drafted RF R. Maris in the 2010 inaugural draft (Round 16, Pick 29, 479th overall Pick). |
| Drafted MR G. Minton in the 2010 inaugural draft (Round 17, Pick 2, 482nd overall Pick). |
| Drafted C J. Romano in the 2010 inaugural draft (Round 18, Pick 29, 539th overall Pick). |
| Drafted SP W. Dismukes in the 2010 inaugural draft (Round 19, Pick 2, 542nd overall Pick). |
| Drafted RF W. Post in the 2010 inaugural draft (Round 20, Pick 29, 599th overall Pick). |
| Drafted RF D. Ennis in the 2010 inaugural draft (Round 21, Pick 2, 602nd overall Pick). |
| Drafted RF J. Heath in the 2010 inaugural draft (Round 22, Pick 29, 659th overall Pick). |
| Drafted 1B J. Bottomley in the 2010 inaugural draft (Round 23, Pick 2, 662nd overall Pick). |
| Drafted 3B H. Thompson in the 2010 inaugural draft (Round 24, Pick 29, 719th overall Pick). |
| Drafted SP P. Jarvis in the 2010 inaugural draft (Round 25, Pick 2, 722nd overall Pick). |
| Drafted 3B H. Carpenter in the 2010 inaugural draft (Round 26, Pick 29, 779th overall Pick). |
| Drafted 2B L. Whitaker in the 2010 inaugural draft (Round 27, Pick 2, 782nd overall Pick). |
| Drafted RF K. Singleton in the 2010 inaugural draft (Round 28, Pick 29, 839th overall Pick). |
| Drafted SS D. Decinces in the 2010 inaugural draft (Round 29, Pick 2, 842nd overall Pick). |
| Drafted LF B. Cerv in the 2010 inaugural draft (Round 30, Pick 29, 899th overall Pick). |
| Drafted SP J. Vander Meer in the 2010 inaugural draft (Round 31, Pick 2, 902nd overall Pick). |
| Drafted SP R. Reuschel in the 2010 inaugural draft (Round 32, Pick 29, 959th overall Pick). |
| Drafted SP C. Osteen in the 2010 inaugural draft (Round 33, Pick 2, 962nd overall Pick). |
| Drafted 1B M. Grace in the 2010 inaugural draft (Round 34, Pick 29, 1019th overall Pick). |
| Drafted MR B. Dawley in the 2010 inaugural draft (Round 35, Pick 2, 1022nd overall Pick). |
| Drafted 1B D. Burrus in the 2010 inaugural draft (Round 36, Pick 29, 1079th overall Pick). |
| Drafted CL J. Mesa in the 2010 inaugural draft (Round 37, Pick 2, 1082nd overall Pick). |
| Drafted 1B D. Bissonette in the 2010 inaugural draft (Round 38, Pick 29, 1139th overall Pick). |
| Drafted MR S. Bedrosian in the 2010 inaugural draft (Round 39, Pick 2, 1142nd overall Pick). |
| Drafted RF L. Piniella in the 2010 inaugural draft (Round 40, Pick 29, 1199th overall Pick). |
| Drafted 2B M. Stock in the 2010 inaugural draft (Round 41, Pick 2, 1202nd overall Pick). |
