| Friday, January 1st, 2010 |
| Drafted CF P. Browning in the 2010 inaugural draft (Round 1, Pick 20, 20th overall Pick). |
| Drafted 3B G. Brett in the 2010 inaugural draft (Round 2, Pick 11, 41st overall Pick). |
| Drafted SS N. Lajoie in the 2010 inaugural draft (Round 3, Pick 20, 80th overall Pick). |
| Drafted SP C. Fisher in the 2010 inaugural draft (Round 4, Pick 11, 101st overall Pick). |
| Drafted SP M. Brown in the 2010 inaugural draft (Round 5, Pick 20, 140th overall Pick). |
| Drafted SP C. Sweeney in the 2010 inaugural draft (Round 6, Pick 11, 161st overall Pick). |
| Drafted RF K. Cuyler in the 2010 inaugural draft (Round 7, Pick 20, 200th overall Pick). |
| Drafted C J. Clements in the 2010 inaugural draft (Round 8, Pick 11, 221st overall Pick). |
| Drafted 1B K. Mitchell in the 2010 inaugural draft (Round 9, Pick 20, 260th overall Pick). |
| Drafted CL J. Wood in the 2010 inaugural draft (Round 10, Pick 11, 281st overall Pick). |
| Drafted 2B S. Sax in the 2010 inaugural draft (Round 11, Pick 20, 320th overall Pick). |
| Drafted LF T. Francona in the 2010 inaugural draft (Round 12, Pick 11, 341st overall Pick). |
| Drafted MR K. Wilhelm in the 2010 inaugural draft (Round 13, Pick 20, 380th overall Pick). |
| Drafted MR H. Brecheen in the 2010 inaugural draft (Round 14, Pick 11, 401st overall Pick). |
| Drafted MR L. Gura in the 2010 inaugural draft (Round 15, Pick 20, 440th overall Pick). |
| Drafted SP B. Grimes in the 2010 inaugural draft (Round 16, Pick 11, 461st overall Pick). |
| Drafted MR J. Pizarro in the 2010 inaugural draft (Round 17, Pick 20, 500th overall Pick). |
| Drafted SP R. Ames in the 2010 inaugural draft (Round 18, Pick 11, 521st overall Pick). |
| Drafted C F. Pytlak in the 2010 inaugural draft (Round 19, Pick 20, 560th overall Pick). |
| Drafted LF C. Reynolds in the 2010 inaugural draft (Round 20, Pick 11, 581st overall Pick). |
| Drafted SS H. Hendrick in the 2010 inaugural draft (Round 21, Pick 20, 620th overall Pick). |
| Drafted RF D. Bichette in the 2010 inaugural draft (Round 22, Pick 11, 641st overall Pick). |
| Drafted RF P. Fox in the 2010 inaugural draft (Round 23, Pick 20, 680th overall Pick). |
| Drafted SS K. Elberfeld in the 2010 inaugural draft (Round 24, Pick 11, 701st overall Pick). |
| Drafted 2B S. Stirnweiss in the 2010 inaugural draft (Round 25, Pick 20, 740th overall Pick). |
| Drafted 3B O. Hale in the 2010 inaugural draft (Round 26, Pick 11, 761st overall Pick). |
| Drafted RF G. Case in the 2010 inaugural draft (Round 27, Pick 20, 800th overall Pick). |
| Drafted 2B B. Cree in the 2010 inaugural draft (Round 28, Pick 11, 821st overall Pick). |
| Drafted SP C. Falkenberg in the 2010 inaugural draft (Round 29, Pick 20, 860th overall Pick). |
| Drafted C D. McGuire in the 2010 inaugural draft (Round 30, Pick 11, 881st overall Pick). |
| Drafted CF L. Dykstra in the 2010 inaugural draft (Round 31, Pick 20, 920th overall Pick). |
| Drafted SS J. Denny in the 2010 inaugural draft (Round 32, Pick 11, 941st overall Pick). |
| Drafted SP T. Hughes in the 2010 inaugural draft (Round 33, Pick 20, 980th overall Pick). |
| Drafted MR R. Myers in the 2010 inaugural draft (Round 34, Pick 11, 1001st overall Pick). |
| Drafted CL T. Forster in the 2010 inaugural draft (Round 35, Pick 20, 1040th overall Pick). |
| Drafted SP J. Quinn in the 2010 inaugural draft (Round 36, Pick 11, 1061st overall Pick). |
| Drafted SP D. Luque in the 2010 inaugural draft (Round 37, Pick 20, 1100th overall Pick). |
| Drafted LF R. Garr in the 2010 inaugural draft (Round 38, Pick 11, 1121st overall Pick). |
| Drafted 1B J. Kruk in the 2010 inaugural draft (Round 39, Pick 20, 1160th overall Pick). |
| Drafted LF J. O'Rourke in the 2010 inaugural draft (Round 40, Pick 11, 1181st overall Pick). |
