| Friday, January 1st, 2010 |
| Drafted CF W. Mays in the 2010 inaugural draft (Round 1, Pick 7, 7th overall Pick). |
| Drafted 2B D. Moore in the 2010 inaugural draft (Round 2, Pick 24, 54th overall Pick). |
| Drafted SS G. Demontreville in the 2010 inaugural draft (Round 3, Pick 7, 67th overall Pick). |
| Drafted SP T. Ramsey in the 2010 inaugural draft (Round 4, Pick 24, 114th overall Pick). |
| Drafted SP R. Nelson in the 2010 inaugural draft (Round 5, Pick 7, 127th overall Pick). |
| Drafted MR E. Moore in the 2010 inaugural draft (Round 6, Pick 24, 174th overall Pick). |
| Drafted RF W. Keeler in the 2010 inaugural draft (Round 7, Pick 7, 187th overall Pick). |
| Drafted SP J. Tudor in the 2010 inaugural draft (Round 8, Pick 24, 234th overall Pick). |
| Drafted 1B H. Heilmann in the 2010 inaugural draft (Round 9, Pick 7, 247th overall Pick). |
| Drafted 3B R. Bresnahan in the 2010 inaugural draft (Round 10, Pick 24, 294th overall Pick). |
| Drafted C S. Hogan in the 2010 inaugural draft (Round 11, Pick 7, 307th overall Pick). |
| Drafted SP D. Righetti in the 2010 inaugural draft (Round 12, Pick 24, 354th overall Pick). |
| Drafted SP D. Hall in the 2010 inaugural draft (Round 13, Pick 7, 367th overall Pick). |
| Drafted MR O. Hess in the 2010 inaugural draft (Round 14, Pick 24, 414th overall Pick). |
| Drafted LF R. Henderson in the 2010 inaugural draft (Round 15, Pick 7, 427th overall Pick). |
| Drafted CL B. Caudill in the 2010 inaugural draft (Round 16, Pick 24, 474th overall Pick). |
| Drafted MR G. Peters in the 2010 inaugural draft (Round 17, Pick 7, 487th overall Pick). |
| Drafted C O. Schreckengost in the 2010 inaugural draft (Round 18, Pick 24, 534th overall Pick). |
| Drafted MR B. Mathews in the 2010 inaugural draft (Round 19, Pick 7, 547th overall Pick). |
| Drafted LF A. Wingo in the 2010 inaugural draft (Round 20, Pick 24, 594th overall Pick). |
| Drafted RF K. Gibson in the 2010 inaugural draft (Round 21, Pick 7, 607th overall Pick). |
| Drafted CF W. Moses in the 2010 inaugural draft (Round 22, Pick 24, 654th overall Pick). |
| Drafted LF G. Bell in the 2010 inaugural draft (Round 23, Pick 7, 667th overall Pick). |
| Drafted SP A. Orth in the 2010 inaugural draft (Round 24, Pick 24, 714th overall Pick). |
| Drafted SP V. Blue in the 2010 inaugural draft (Round 25, Pick 7, 727th overall Pick). |
| Drafted SP H. Coveleski in the 2010 inaugural draft (Round 26, Pick 24, 774th overall Pick). |
| Drafted RF G. Case in the 2010 inaugural draft (Round 27, Pick 7, 787th overall Pick). |
| Drafted 1B G. Hodges in the 2010 inaugural draft (Round 28, Pick 24, 834th overall Pick). |
| Drafted SP J. Powell in the 2010 inaugural draft (Round 29, Pick 7, 847th overall Pick). |
| Drafted SS D. Menke in the 2010 inaugural draft (Round 30, Pick 24, 894th overall Pick). |
| Drafted 3B S. Hack in the 2010 inaugural draft (Round 31, Pick 7, 907th overall Pick). |
| Drafted C R. Schalk in the 2010 inaugural draft (Round 32, Pick 24, 954th overall Pick). |
| Drafted CF L. Dykstra in the 2010 inaugural draft (Round 33, Pick 7, 967th overall Pick). |
| Drafted 2B R. Schoendienst in the 2010 inaugural draft (Round 34, Pick 24, 1014th overall Pick). |
| Drafted MR R. Myers in the 2010 inaugural draft (Round 35, Pick 7, 1027th overall Pick). |
| Drafted LF W. Moon in the 2010 inaugural draft (Round 36, Pick 24, 1074th overall Pick). |
| Drafted MR B. Thigpen in the 2010 inaugural draft (Round 37, Pick 7, 1087th overall Pick). |
| Drafted SP H. Pennock in the 2010 inaugural draft (Round 38, Pick 24, 1134th overall Pick). |
| Drafted CL R. Fingers in the 2010 inaugural draft (Round 39, Pick 7, 1147th overall Pick). |
| Drafted RF B. Ewing in the 2010 inaugural draft (Round 40, Pick 24, 1194th overall Pick). |
| Drafted 1B G. Schaefer in the 2010 inaugural draft (Round 41, Pick 7, 1207th overall Pick). |
| Purchased the contract of CL R. Fingers from Triple A Brooklyn. |
| Purchased the contract of MR R. Myers from Triple A Brooklyn. |
| Purchased the contract of SP J. Powell from Triple A Brooklyn. |
| Purchased the contract of SP H. Coveleski from Triple A Brooklyn. |
| Purchased the contract of 1B G. Hodges from Triple A Brooklyn. |
| Purchased the contract of 2B R. Schoendienst from Triple A Brooklyn. |
| Demoted MR O. Hess to Triple A Brooklyn. |
| Demoted SP D. Righetti to Triple A Brooklyn. |
| Demoted SP V. Blue to Triple A Brooklyn. |
| Demoted CL B. Caudill to Triple A Brooklyn. |
| Demoted CF W. Moses to Triple A Brooklyn. |
| Demoted RF K. Gibson to Triple A Brooklyn. |
| Demoted C R. Schalk from Triple A Brooklyn to Double A Galveston. |
