| Friday, January 1st, 2010 |
| Drafted 2B R. Barnes in the 2010 inaugural draft (Round 1, Pick 12, 12th overall Pick). |
| Drafted C B. Petway in the 2010 inaugural draft (Round 2, Pick 19, 49th overall Pick). |
| Drafted RF T. Stearns in the 2010 inaugural draft (Round 3, Pick 12, 72nd overall Pick). |
| Drafted SP J. Pfiester in the 2010 inaugural draft (Round 4, Pick 19, 109th overall Pick). |
| Drafted SP T. Abernathy in the 2010 inaugural draft (Round 5, Pick 12, 132nd overall Pick). |
| Drafted CF H. Mueller in the 2010 inaugural draft (Round 6, Pick 19, 169th overall Pick). |
| Drafted SP J. McGinnis in the 2010 inaugural draft (Round 7, Pick 12, 192nd overall Pick). |
| Drafted 1B M. McGwire in the 2010 inaugural draft (Round 8, Pick 19, 229th overall Pick). |
| Drafted LF K. Williams in the 2010 inaugural draft (Round 9, Pick 12, 252nd overall Pick). |
| Drafted SP D. Shaw in the 2010 inaugural draft (Round 10, Pick 19, 289th overall Pick). |
| Drafted SP N. Maddox in the 2010 inaugural draft (Round 11, Pick 12, 312nd overall Pick). |
| Drafted MR H. Eller in the 2010 inaugural draft (Round 12, Pick 19, 349th overall Pick). |
| Drafted CL W. Hernandez in the 2010 inaugural draft (Round 13, Pick 12, 372nd overall Pick). |
| Drafted SS E. McKean in the 2010 inaugural draft (Round 14, Pick 19, 409th overall Pick). |
| Drafted 3B K. Keltner in the 2010 inaugural draft (Round 15, Pick 12, 432nd overall Pick). |
| Drafted MR J. Bell in the 2010 inaugural draft (Round 16, Pick 19, 469th overall Pick). |
| Drafted MR S. Sallee in the 2010 inaugural draft (Round 17, Pick 12, 492nd overall Pick). |
| Drafted CL H. Daily in the 2010 inaugural draft (Round 18, Pick 19, 529th overall Pick). |
| Drafted CL R. Perranoski in the 2010 inaugural draft (Round 19, Pick 12, 552nd overall Pick). |
| Drafted C F. Snyder in the 2010 inaugural draft (Round 20, Pick 19, 589th overall Pick). |
| Drafted MR G. Garber in the 2010 inaugural draft (Round 21, Pick 12, 612nd overall Pick). |
| Drafted LF T. Raines in the 2010 inaugural draft (Round 22, Pick 19, 649th overall Pick). |
| Drafted RF T. Holmes in the 2010 inaugural draft (Round 23, Pick 12, 672nd overall Pick). |
| Drafted SP T. Bonham in the 2010 inaugural draft (Round 24, Pick 19, 709th overall Pick). |
| Drafted SS A. Fletcher in the 2010 inaugural draft (Round 25, Pick 12, 732nd overall Pick). |
| Drafted LF R. Blades in the 2010 inaugural draft (Round 26, Pick 19, 769th overall Pick). |
| Drafted C J. Wilson in the 2010 inaugural draft (Round 27, Pick 12, 792nd overall Pick). |
| Drafted SP T. Higuera in the 2010 inaugural draft (Round 28, Pick 19, 829th overall Pick). |
| Drafted RF C. Furillo in the 2010 inaugural draft (Round 29, Pick 12, 852nd overall Pick). |
| Drafted SP W. Wood in the 2010 inaugural draft (Round 30, Pick 19, 889th overall Pick). |
| Drafted CL B. Adams in the 2010 inaugural draft (Round 31, Pick 12, 912nd overall Pick). |
| Drafted CF H. Felsch in the 2010 inaugural draft (Round 32, Pick 19, 949th overall Pick). |
| Drafted SP C. Falkenberg in the 2010 inaugural draft (Round 33, Pick 12, 972nd overall Pick). |
| Drafted 1B M. Grace in the 2010 inaugural draft (Round 34, Pick 19, 1009th overall Pick). |
| Drafted SS G. Disarcina in the 2010 inaugural draft (Round 35, Pick 12, 1032nd overall Pick). |
| Drafted 2B E. Stanky in the 2010 inaugural draft (Round 36, Pick 19, 1069th overall Pick). |
| Drafted SP D. Kerr in the 2010 inaugural draft (Round 37, Pick 12, 1092nd overall Pick). |
| Drafted 3B G. Nettles in the 2010 inaugural draft (Round 38, Pick 19, 1129th overall Pick). |
| Drafted CL D. Knowles in the 2010 inaugural draft (Round 39, Pick 12, 1152nd overall Pick). |
| Drafted SS P. Rizzuto in the 2010 inaugural draft (Round 40, Pick 19, 1189th overall Pick). |
| Purchased the contract of CL B. Adams from Triple A Toledo. |
| Purchased the contract of SP T. Higuera from Triple A Toledo. |
| Purchased the contract of SP W. Wood from Triple A Toledo. |
| Purchased the contract of SP C. Falkenberg from Triple A Toledo. |
| Purchased the contract of RF C. Furillo from Triple A Toledo. |
| Purchased the contract of 2B E. Stanky from Triple A Toledo. |
| Purchased the contract of SS P. Rizzuto from Triple A Toledo. |
| Demoted SP N. Maddox to Triple A Toledo. |
| Demoted MR J. Bell to Triple A Toledo. |
| Demoted MR G. Garber to Triple A Toledo. |
| Demoted CL H. Daily to Triple A Toledo. |
| Demoted CL R. Perranoski to Triple A Toledo. |
| Demoted CF H. Mueller to Triple A Toledo. |
| Demoted SS A. Fletcher to Triple A Toledo. |
