| Friday, January 1st, 2010 |
| Drafted 1B F. Thomas in the 2010 inaugural draft (Round 1, Pick 5, 5th overall Pick). |
| Drafted C B. Delancey in the 2010 inaugural draft (Round 2, Pick 26, 56th overall Pick). |
| Drafted 2B F. Dunlap in the 2010 inaugural draft (Round 3, Pick 5, 65th overall Pick). |
| Drafted SP G. Hecker in the 2010 inaugural draft (Round 4, Pick 26, 116th overall Pick). |
| Drafted SP J. Clarkson in the 2010 inaugural draft (Round 5, Pick 5, 125th overall Pick). |
| Drafted LF C. Keller in the 2010 inaugural draft (Round 6, Pick 26, 176th overall Pick). |
| Drafted SP D. Burns in the 2010 inaugural draft (Round 7, Pick 5, 185th overall Pick). |
| Drafted SS L. Cross in the 2010 inaugural draft (Round 8, Pick 26, 236th overall Pick). |
| Drafted RF T. Gwynn in the 2010 inaugural draft (Round 9, Pick 5, 245th overall Pick). |
| Drafted MR P. Perritt in the 2010 inaugural draft (Round 10, Pick 26, 296th overall Pick). |
| Drafted MR R. Works in the 2010 inaugural draft (Round 11, Pick 5, 305th overall Pick). |
| Drafted SP E. Siever in the 2010 inaugural draft (Round 12, Pick 26, 356th overall Pick). |
| Drafted 3B T. Perez in the 2010 inaugural draft (Round 13, Pick 5, 365th overall Pick). |
| Drafted CF M. Griffin in the 2010 inaugural draft (Round 14, Pick 26, 416th overall Pick). |
| Drafted MR M. Cuellar in the 2010 inaugural draft (Round 15, Pick 5, 425th overall Pick). |
| Drafted MR D. Baldwin in the 2010 inaugural draft (Round 16, Pick 26, 476th overall Pick). |
| Drafted MR M. Marshall in the 2010 inaugural draft (Round 17, Pick 5, 485th overall Pick). |
| Drafted C J. Romano in the 2010 inaugural draft (Round 18, Pick 26, 536th overall Pick). |
| Drafted SP J. Tannehill in the 2010 inaugural draft (Round 19, Pick 5, 545th overall Pick). |
| Drafted RF S. Lezcano in the 2010 inaugural draft (Round 20, Pick 26, 596th overall Pick). |
| Drafted RF J. Cassidy in the 2010 inaugural draft (Round 21, Pick 5, 605th overall Pick). |
| Drafted 2B B. Johnson in the 2010 inaugural draft (Round 22, Pick 26, 656th overall Pick). |
| Drafted CF K. Puckett in the 2010 inaugural draft (Round 23, Pick 5, 665th overall Pick). |
| Drafted SP D. McLain in the 2010 inaugural draft (Round 24, Pick 26, 716th overall Pick). |
| Drafted 2B N. Fox in the 2010 inaugural draft (Round 25, Pick 5, 725th overall Pick). |
| Drafted SP W. Hacker in the 2010 inaugural draft (Round 26, Pick 26, 776th overall Pick). |
| Drafted CF B. Jackson in the 2010 inaugural draft (Round 27, Pick 5, 785th overall Pick). |
| Drafted LF B. Fothergill in the 2010 inaugural draft (Round 28, Pick 26, 836th overall Pick). |
| Drafted C C. Anson in the 2010 inaugural draft (Round 29, Pick 5, 845th overall Pick). |
| Drafted SS D. Bancroft in the 2010 inaugural draft (Round 30, Pick 26, 896th overall Pick). |
| Drafted 2B F. Thompson in the 2010 inaugural draft (Round 31, Pick 5, 905th overall Pick). |
| Drafted 1B J. Daubert in the 2010 inaugural draft (Round 32, Pick 26, 956th overall Pick). |
| Drafted 3B H. Carpenter in the 2010 inaugural draft (Round 33, Pick 5, 965th overall Pick). |
| Drafted RF J. Stone in the 2010 inaugural draft (Round 34, Pick 26, 1016th overall Pick). |
| Drafted MR D. Mossi in the 2010 inaugural draft (Round 35, Pick 5, 1025th overall Pick). |
| Drafted MR T. Adams in the 2010 inaugural draft (Round 36, Pick 26, 1076th overall Pick). |
| Drafted SP J. Healy in the 2010 inaugural draft (Round 37, Pick 5, 1085th overall Pick). |
| Drafted SP A. Maul in the 2010 inaugural draft (Round 38, Pick 26, 1136th overall Pick). |
| Drafted CL M. Clear in the 2010 inaugural draft (Round 39, Pick 5, 1145th overall Pick). |
| Drafted 2B B. Ferguson in the 2010 inaugural draft (Round 40, Pick 26, 1196th overall Pick). |
| Drafted LF R. Radcliff in the 2010 inaugural draft (Round 41, Pick 5, 1205th overall Pick). |
| Purchased the contract of MR D. Mossi from Triple A Memphis. |
| Purchased the contract of SP W. Hacker from Triple A Memphis. |
| Purchased the contract of C C. Anson from Triple A Memphis. |
| Purchased the contract of SS D. Bancroft from Triple A Memphis. |
| Purchased the contract of 1B J. Daubert from Triple A Memphis. |
| Purchased the contract of 2B B. Ferguson from Triple A Memphis. |
| Demoted SP D. McLain to Triple A Memphis. |
| Demoted C J. Romano to Triple A Memphis. |
| Demoted 2B B. Johnson to Triple A Memphis. |
| Demoted CF K. Puckett to Triple A Memphis. |
| Demoted 2B N. Fox to Triple A Memphis. |
| Demoted 3B H. Carpenter from Triple A Memphis to Double A Nashville. |
| Demoted RF J. Cassidy to Double A Nashville. |
