| Friday, January 1st, 2010 |
| Drafted CF S. Poles in the 2010 inaugural draft (Round 1, Pick 21, 21st overall Pick). |
| Drafted LF K. Daniels in the 2010 inaugural draft (Round 2, Pick 10, 40th overall Pick). |
| Drafted 1B H. Zimmerman in the 2010 inaugural draft (Round 3, Pick 21, 81st overall Pick). |
| Drafted SP R. Ford in the 2010 inaugural draft (Round 4, Pick 10, 100th overall Pick). |
| Drafted SP D. Rudolph in the 2010 inaugural draft (Round 5, Pick 21, 141st overall Pick). |
| Drafted SS W. English in the 2010 inaugural draft (Round 6, Pick 10, 160th overall Pick). |
| Drafted SP R. Brown in the 2010 inaugural draft (Round 7, Pick 21, 201st overall Pick). |
| Drafted 3B M. Schmidt in the 2010 inaugural draft (Round 8, Pick 10, 220th overall Pick). |
| Drafted SP C. Buffinton in the 2010 inaugural draft (Round 9, Pick 21, 261st overall Pick). |
| Drafted SP D. Davenport in the 2010 inaugural draft (Round 10, Pick 10, 280th overall Pick). |
| Drafted C D. Padgett in the 2010 inaugural draft (Round 11, Pick 21, 321st overall Pick). |
| Drafted RF J. Rice in the 2010 inaugural draft (Round 12, Pick 10, 340th overall Pick). |
| Drafted 2B J. Evers in the 2010 inaugural draft (Round 13, Pick 21, 381st overall Pick). |
| Drafted CL M. Prendergast in the 2010 inaugural draft (Round 14, Pick 10, 400th overall Pick). |
| Drafted MR J. Marichal in the 2010 inaugural draft (Round 15, Pick 21, 441st overall Pick). |
| Drafted MR J. Key in the 2010 inaugural draft (Round 16, Pick 10, 460th overall Pick). |
| Drafted CL T. Bond in the 2010 inaugural draft (Round 17, Pick 21, 501st overall Pick). |
| Drafted CL J. Reardon in the 2010 inaugural draft (Round 18, Pick 10, 520th overall Pick). |
| Drafted MR D. McMahon in the 2010 inaugural draft (Round 19, Pick 21, 561st overall Pick). |
| Drafted C A. Robinson in the 2010 inaugural draft (Round 20, Pick 10, 580th overall Pick). |
| Drafted MR J. Thompson in the 2010 inaugural draft (Round 21, Pick 21, 621st overall Pick). |
| Drafted LF F. Nicholson in the 2010 inaugural draft (Round 22, Pick 10, 640th overall Pick). |
| Drafted 1B A. Thornton in the 2010 inaugural draft (Round 23, Pick 21, 681st overall Pick). |
| Drafted 3B O. Hale in the 2010 inaugural draft (Round 24, Pick 10, 700th overall Pick). |
| Drafted 1B F. McGriff in the 2010 inaugural draft (Round 25, Pick 21, 741st overall Pick). |
| Drafted SP G. Zettlein in the 2010 inaugural draft (Round 26, Pick 10, 760th overall Pick). |
| Drafted 3B L. Marr in the 2010 inaugural draft (Round 27, Pick 21, 801st overall Pick). |
| Drafted SS J. Denny in the 2010 inaugural draft (Round 28, Pick 10, 820th overall Pick). |
| Drafted C W. Schang in the 2010 inaugural draft (Round 29, Pick 21, 861st overall Pick). |
| Drafted MR R. Kline in the 2010 inaugural draft (Round 30, Pick 10, 880th overall Pick). |
| Drafted SP E. Cushman in the 2010 inaugural draft (Round 31, Pick 21, 921st overall Pick). |
| Drafted 2B A. High in the 2010 inaugural draft (Round 32, Pick 10, 940th overall Pick). |
| Drafted RF B. Bell in the 2010 inaugural draft (Round 33, Pick 21, 981st overall Pick). |
| Drafted CL U. Urbina in the 2010 inaugural draft (Round 34, Pick 10, 1000th overall Pick). |
| Drafted SP G. Kaiserling in the 2010 inaugural draft (Round 35, Pick 21, 1041st overall Pick). |
| Drafted LF B. Cerv in the 2010 inaugural draft (Round 36, Pick 10, 1060th overall Pick). |
| Drafted CL D. Ward in the 2010 inaugural draft (Round 37, Pick 21, 1101st overall Pick). |
| Drafted SP R. Faber in the 2010 inaugural draft (Round 38, Pick 10, 1120th overall Pick). |
| Drafted CL H. Wilhelm in the 2010 inaugural draft (Round 39, Pick 21, 1161st overall Pick). |
| Drafted LF J. Cardenal in the 2010 inaugural draft (Round 40, Pick 10, 1180th overall Pick). |
| Purchased the contract of SP G. Zettlein from Triple A South Shore. |
| Purchased the contract of CL H. Wilhelm from Triple A South Shore. |
| Purchased the contract of CL U. Urbina from Triple A South Shore. |
| Purchased the contract of MR R. Kline from Triple A South Shore. |
| Purchased the contract of C W. Schang from Triple A South Shore. |
| Purchased the contract of LF B. Cerv from Triple A South Shore. |
| Purchased the contract of SS J. Denny from Triple A South Shore. |
| Demoted SP R. Brown to Triple A South Shore. |
| Demoted MR D. McMahon to Triple A South Shore. |
| Demoted CL J. Reardon to Triple A South Shore. |
| Demoted MR J. Thompson to Triple A South Shore. |
| Demoted C A. Robinson to Triple A South Shore. |
| Demoted 3B O. Hale to Triple A South Shore. |
| Demoted 1B A. Thornton to Triple A South Shore. |
