| Friday, January 1st, 2010 |
| Drafted 1B B. Taylor in the 2010 inaugural draft (Round 1, Pick 19, 19th overall Pick). |
| Drafted CF T. Cobb in the 2010 inaugural draft (Round 2, Pick 12, 42nd overall Pick). |
| Drafted SS N. Lajoie in the 2010 inaugural draft (Round 3, Pick 19, 79th overall Pick). |
| Drafted SP C. Hubbell in the 2010 inaugural draft (Round 4, Pick 12, 102nd overall Pick). |
| Drafted SP P. Werden in the 2010 inaugural draft (Round 5, Pick 19, 139th overall Pick). |
| Drafted SP J. Ward in the 2010 inaugural draft (Round 6, Pick 12, 162nd overall Pick). |
| Drafted SP G. McQuillan in the 2010 inaugural draft (Round 7, Pick 19, 199th overall Pick). |
| Drafted SP F. Anderson in the 2010 inaugural draft (Round 8, Pick 12, 222nd overall Pick). |
| Drafted 3B W. Kurowski in the 2010 inaugural draft (Round 9, Pick 19, 259th overall Pick). |
| Drafted MR S. Wiedman in the 2010 inaugural draft (Round 10, Pick 12, 282nd overall Pick). |
| Drafted RF T. Salmon in the 2010 inaugural draft (Round 11, Pick 19, 319th overall Pick). |
| Drafted C E. McFarland in the 2010 inaugural draft (Round 12, Pick 12, 342nd overall Pick). |
| Drafted CL D. Vance in the 2010 inaugural draft (Round 13, Pick 19, 379th overall Pick). |
| Drafted LF W. Stargell in the 2010 inaugural draft (Round 14, Pick 12, 402nd overall Pick). |
| Drafted MR B. Lee in the 2010 inaugural draft (Round 15, Pick 19, 439th overall Pick). |
| Drafted 2B B. Keister in the 2010 inaugural draft (Round 16, Pick 12, 462nd overall Pick). |
| Drafted MR T. Stoddard in the 2010 inaugural draft (Round 17, Pick 19, 499th overall Pick). |
| Drafted C D. Porter in the 2010 inaugural draft (Round 18, Pick 12, 522nd overall Pick). |
| Drafted MR M. Lopez in the 2010 inaugural draft (Round 19, Pick 19, 559th overall Pick). |
| Drafted RF G. Gore in the 2010 inaugural draft (Round 20, Pick 12, 582nd overall Pick). |
| Drafted LF B. Falk in the 2010 inaugural draft (Round 21, Pick 19, 619th overall Pick). |
| Drafted RF D. Bichette in the 2010 inaugural draft (Round 22, Pick 12, 642nd overall Pick). |
| Drafted 3B B. Werber in the 2010 inaugural draft (Round 23, Pick 19, 679th overall Pick). |
| Drafted SP F. Toney in the 2010 inaugural draft (Round 24, Pick 12, 702nd overall Pick). |
| Drafted SP J. Bagby in the 2010 inaugural draft (Round 25, Pick 19, 739th overall Pick). |
| Drafted 1B J. Anderson in the 2010 inaugural draft (Round 26, Pick 12, 762nd overall Pick). |
| Drafted MR L. Arroyo in the 2010 inaugural draft (Round 27, Pick 19, 799th overall Pick). |
| Drafted SP L. Cheney in the 2010 inaugural draft (Round 28, Pick 12, 822nd overall Pick). |
| Drafted C C. Zimmer in the 2010 inaugural draft (Round 29, Pick 19, 859th overall Pick). |
| Drafted SS O. Smith in the 2010 inaugural draft (Round 30, Pick 12, 882nd overall Pick). |
| Drafted SP B. Moose in the 2010 inaugural draft (Round 31, Pick 19, 919th overall Pick). |
| Drafted SP M. Garcia in the 2010 inaugural draft (Round 32, Pick 12, 942nd overall Pick). |
| Drafted CF R. Oldring in the 2010 inaugural draft (Round 33, Pick 19, 979th overall Pick). |
| Drafted 3B B. Weaver in the 2010 inaugural draft (Round 34, Pick 12, 1002nd overall Pick). |
| Drafted RF J. Hickman in the 2010 inaugural draft (Round 35, Pick 19, 1039th overall Pick). |
| Drafted 2B W. Fisler in the 2010 inaugural draft (Round 36, Pick 12, 1062nd overall Pick). |
| Drafted MR E. Watt in the 2010 inaugural draft (Round 37, Pick 19, 1099th overall Pick). |
| Drafted CL R. Nen in the 2010 inaugural draft (Round 38, Pick 12, 1122nd overall Pick). |
| Drafted CL D. Lamp in the 2010 inaugural draft (Round 39, Pick 19, 1159th overall Pick). |
| Drafted LF M. Minoso in the 2010 inaugural draft (Round 40, Pick 12, 1182nd overall Pick). |
| Purchased the contract of CL R. Nen from Triple A La Porte. |
| Purchased the contract of SP L. Cheney from Triple A La Porte. |
| Purchased the contract of MR L. Arroyo from Triple A La Porte. |
| Purchased the contract of CL D. Lamp from Triple A La Porte. |
| Purchased the contract of C C. Zimmer from Triple A La Porte. |
| Purchased the contract of SS O. Smith from Triple A La Porte. |
| Purchased the contract of RF J. Hickman from Triple A La Porte. |
| Purchased the contract of 3B M. Minoso from Triple A La Porte. |
| Purchased the contract of 2B W. Fisler from Triple A La Porte. |
| Demoted SP J. Bagby to Triple A La Porte. |
| Demoted MR S. Wiedman to Triple A La Porte. |
| Demoted MR M. Lopez to Triple A La Porte. |
| Demoted MR T. Stoddard to Triple A La Porte. |
| Demoted C E. McFarland to Triple A La Porte. |
| Demoted RF G. Gore to Triple A La Porte. |
| Demoted 2B B. Keister to Triple A La Porte. |
| Demoted 3B B. Werber to Triple A La Porte. |
| Demoted LF B. Falk to Triple A La Porte. |
| Demoted CF R. Oldring from Triple A La Porte to Double A Baytown. |
