| Friday, January 1st, 2010 |
| Drafted RF B. Kauff in the 2010 inaugural draft (Round 1, Pick 23, 23rd overall Pick). |
| Drafted LF J. Kelley in the 2010 inaugural draft (Round 2, Pick 8, 38th overall Pick). |
| Drafted 3B J. Sheckard in the 2010 inaugural draft (Round 3, Pick 23, 83rd overall Pick). |
| Drafted SP C. Young in the 2010 inaugural draft (Round 4, Pick 8, 98th overall Pick). |
| Drafted SP E. Seward in the 2010 inaugural draft (Round 5, Pick 23, 143rd overall Pick). |
| Drafted SS H. Jennings in the 2010 inaugural draft (Round 6, Pick 8, 158th overall Pick). |
| Drafted SP R. Collins in the 2010 inaugural draft (Round 7, Pick 23, 203rd overall Pick). |
| Drafted 2B G. Watkins in the 2010 inaugural draft (Round 8, Pick 8, 218th overall Pick). |
| Drafted SP J. Taylor in the 2010 inaugural draft (Round 9, Pick 23, 263rd overall Pick). |
| Drafted C Y. Berra in the 2010 inaugural draft (Round 10, Pick 8, 278th overall Pick). |
| Drafted 1B D. Evans in the 2010 inaugural draft (Round 11, Pick 23, 323rd overall Pick). |
| Drafted MR R. Roberts in the 2010 inaugural draft (Round 12, Pick 8, 338th overall Pick). |
| Drafted MR J. Coombs in the 2010 inaugural draft (Round 13, Pick 23, 383rd overall Pick). |
| Drafted MR H. Brecheen in the 2010 inaugural draft (Round 14, Pick 8, 398th overall Pick). |
| Drafted MR A. McBean in the 2010 inaugural draft (Round 15, Pick 23, 443rd overall Pick). |
| Drafted CL G. Olson in the 2010 inaugural draft (Round 16, Pick 8, 458th overall Pick). |
| Drafted CF L. Doby in the 2010 inaugural draft (Round 17, Pick 23, 503rd overall Pick). |
| Drafted SP B. Odom in the 2010 inaugural draft (Round 18, Pick 8, 518th overall Pick). |
| Drafted C S. Alomar, Jr. in the 2010 inaugural draft (Round 19, Pick 23, 563rd overall Pick). |
| Drafted 1B R. Palmeiro in the 2010 inaugural draft (Round 20, Pick 8, 578th overall Pick). |
| Drafted 1B D. Hurst in the 2010 inaugural draft (Round 21, Pick 23, 623rd overall Pick). |
| Drafted CF G. Foster in the 2010 inaugural draft (Round 22, Pick 8, 638th overall Pick). |
| Drafted LF A. McHenry in the 2010 inaugural draft (Round 23, Pick 23, 683rd overall Pick). |
| Drafted LF B. Miller in the 2010 inaugural draft (Round 24, Pick 8, 698th overall Pick). |
| Drafted 2B L. Whitaker in the 2010 inaugural draft (Round 25, Pick 23, 743rd overall Pick). |
| Drafted SP P. Douglas in the 2010 inaugural draft (Round 26, Pick 8, 758th overall Pick). |
| Drafted RF D. Porter in the 2010 inaugural draft (Round 27, Pick 23, 803rd overall Pick). |
| Drafted 1B M. Vernon in the 2010 inaugural draft (Round 28, Pick 8, 818th overall Pick). |
| Drafted SS D. Decinces in the 2010 inaugural draft (Round 29, Pick 23, 863rd overall Pick). |
| Drafted C E. Howard in the 2010 inaugural draft (Round 30, Pick 8, 878th overall Pick). |
| Drafted 2B W. Backman in the 2010 inaugural draft (Round 31, Pick 23, 923rd overall Pick). |
| Drafted LF B. Veach in the 2010 inaugural draft (Round 32, Pick 8, 938th overall Pick). |
| Drafted SP B. Lemon in the 2010 inaugural draft (Round 33, Pick 23, 983rd overall Pick). |
| Drafted SP J. Kaat in the 2010 inaugural draft (Round 34, Pick 8, 998th overall Pick). |
| Drafted 3B J. Tinker in the 2010 inaugural draft (Round 35, Pick 23, 1043rd overall Pick). |
| Drafted MR J. Franco in the 2010 inaugural draft (Round 36, Pick 8, 1058th overall Pick). |
| Drafted 1B H. Larkin in the 2010 inaugural draft (Round 37, Pick 23, 1103rd overall Pick). |
| Drafted 1B D. Orr in the 2010 inaugural draft (Round 38, Pick 8, 1118th overall Pick). |
| Drafted 1B C. Comiskey in the 2010 inaugural draft (Round 39, Pick 23, 1163rd overall Pick). |
| Drafted 1B G. Burns in the 2010 inaugural draft (Round 40, Pick 8, 1178th overall Pick). |
| Purchased the contract of MR J. Franco from Triple A Tipton. |
| Purchased the contract of SP P. Douglas from Triple A Tipton. |
| Purchased the contract of SP B. Lemon from Triple A Tipton. |
| Purchased the contract of C E. Howard from Triple A Tipton. |
| Purchased the contract of RF B. Veach from Triple A Tipton. |
| Purchased the contract of SS D. Decinces from Triple A Tipton. |
| Demoted SP B. Odom to Triple A Tipton. |
| Demoted C S. Alomar, Jr. to Triple A Tipton. |
| Demoted LF B. Miller to Triple A Tipton. |
| Demoted 1B D. Hurst to Triple A Tipton. |
| Demoted 1B D. Evans to Triple A Tipton. |
| Demoted LF A. McHenry to Triple A Tipton. |
| Demoted 1B C. Comiskey from Triple A Tipton to Double A Solon. |
