| Friday, January 1st, 2010 |
| Drafted CF M. Mantle in the 2010 inaugural draft (Round 1, Pick 6, 6th overall Pick). |
| Drafted 1B M. Suttles in the 2010 inaugural draft (Round 2, Pick 25, 55th overall Pick). |
| Drafted SS J. Cronin in the 2010 inaugural draft (Round 3, Pick 6, 66th overall Pick). |
| Drafted SP L. Tiant in the 2010 inaugural draft (Round 4, Pick 25, 115th overall Pick). |
| Drafted SP G. Bradley in the 2010 inaugural draft (Round 5, Pick 6, 126th overall Pick). |
| Drafted LF R. Colavito in the 2010 inaugural draft (Round 6, Pick 25, 175th overall Pick). |
| Drafted SP S. Stratton in the 2010 inaugural draft (Round 7, Pick 6, 186th overall Pick). |
| Drafted SP B. Foster in the 2010 inaugural draft (Round 8, Pick 25, 235th overall Pick). |
| Drafted MR K. Tatum in the 2010 inaugural draft (Round 9, Pick 6, 246th overall Pick). |
| Drafted 2B C. Childs in the 2010 inaugural draft (Round 10, Pick 25, 295th overall Pick). |
| Drafted RF B. Hamilton in the 2010 inaugural draft (Round 11, Pick 6, 306th overall Pick). |
| Drafted MR B. Dineen in the 2010 inaugural draft (Round 12, Pick 25, 355th overall Pick). |
| Drafted MR R. Marquard in the 2010 inaugural draft (Round 13, Pick 6, 366th overall Pick). |
| Drafted MR B. Friend in the 2010 inaugural draft (Round 14, Pick 25, 415th overall Pick). |
| Drafted SP P. Galvin in the 2010 inaugural draft (Round 15, Pick 6, 426th overall Pick). |
| Drafted C J. Lapp in the 2010 inaugural draft (Round 16, Pick 25, 475th overall Pick). |
| Drafted 3B J. Williams in the 2010 inaugural draft (Round 17, Pick 6, 486th overall Pick). |
| Drafted C S. Davis in the 2010 inaugural draft (Round 18, Pick 25, 535th overall Pick). |
| Drafted CL T. Murphy in the 2010 inaugural draft (Round 19, Pick 6, 546th overall Pick). |
| Drafted LF B. Goodman in the 2010 inaugural draft (Round 20, Pick 25, 595th overall Pick). |
| Drafted SS G. Wright in the 2010 inaugural draft (Round 21, Pick 6, 606th overall Pick). |
| Drafted SS J. Valentin in the 2010 inaugural draft (Round 22, Pick 25, 655th overall Pick). |
| Drafted SS D. Lundy in the 2010 inaugural draft (Round 23, Pick 6, 666th overall Pick). |
| Drafted SP E. Blackwell in the 2010 inaugural draft (Round 24, Pick 25, 715th overall Pick). |
| Drafted SP D. Roberts in the 2010 inaugural draft (Round 25, Pick 6, 726th overall Pick). |
| Drafted SP M. Lolich in the 2010 inaugural draft (Round 26, Pick 25, 775th overall Pick). |
| Drafted CF P. Hines in the 2010 inaugural draft (Round 27, Pick 6, 786th overall Pick). |
| Drafted 2B Y. Robinson in the 2010 inaugural draft (Round 28, Pick 25, 835th overall Pick). |
| Drafted SS W. Wells in the 2010 inaugural draft (Round 29, Pick 6, 846th overall Pick). |
| Drafted RF D. Walker in the 2010 inaugural draft (Round 30, Pick 25, 895th overall Pick). |
| Drafted 1B B. Freeman in the 2010 inaugural draft (Round 31, Pick 6, 906th overall Pick). |
| Drafted C M. Sanguillen in the 2010 inaugural draft (Round 32, Pick 25, 955th overall Pick). |
| Drafted SP H. Aguirre in the 2010 inaugural draft (Round 33, Pick 6, 966th overall Pick). |
| Drafted 3B D. Prothro in the 2010 inaugural draft (Round 34, Pick 25, 1015th overall Pick). |
| Drafted LF B. Meusel in the 2010 inaugural draft (Round 35, Pick 6, 1026th overall Pick). |
| Drafted MR B. Dawley in the 2010 inaugural draft (Round 36, Pick 25, 1075th overall Pick). |
| Drafted SP C. Cummings in the 2010 inaugural draft (Round 37, Pick 6, 1086th overall Pick). |
| Drafted SP T. Lovett in the 2010 inaugural draft (Round 38, Pick 25, 1135th overall Pick). |
| Drafted CL R. Reed in the 2010 inaugural draft (Round 39, Pick 6, 1146th overall Pick). |
| Drafted RF H. Hooper in the 2010 inaugural draft (Round 40, Pick 25, 1195th overall Pick). |
| Drafted 1B C. Hinton in the 2010 inaugural draft (Round 41, Pick 6, 1206th overall Pick). |
| Purchased the contract of SP H. Aguirre from Triple A Amarillo. |
| Purchased the contract of SP C. Cummings from Triple A Amarillo. |
| Purchased the contract of SS W. Wells from Triple A Amarillo. |
| Purchased the contract of LF D. Walker from Triple A Amarillo. |
| Purchased the contract of RF H. Hooper from Triple A Amarillo. |
| Purchased the contract of RF B. Meusel from Triple A Amarillo. |
| Demoted SP E. Blackwell to Triple A Amarillo. |
| Demoted CL T. Murphy to Triple A Amarillo. |
| Demoted LF B. Goodman to Triple A Amarillo. |
| Demoted SS G. Wright to Triple A Amarillo. |
| Demoted SS J. Valentin to Triple A Amarillo. |
| Demoted 3B J. Williams to Triple A Amarillo. |
