| Friday, January 1st, 2010 |
| Drafted SS N. Garciaparra in the 2010 inaugural draft (Round 1, Pick 22, 22nd overall Pick). |
| Drafted LF H. Rice in the 2010 inaugural draft (Round 2, Pick 9, 39th overall Pick). |
| Drafted CF A. Simmons in the 2010 inaugural draft (Round 3, Pick 22, 82nd overall Pick). |
| Drafted SP E. Steele in the 2010 inaugural draft (Round 4, Pick 9, 99th overall Pick). |
| Drafted SP J. Dygert in the 2010 inaugural draft (Round 5, Pick 22, 142nd overall Pick). |
| Drafted C B. MacKey in the 2010 inaugural draft (Round 6, Pick 9, 159th overall Pick). |
| Drafted SP D. Gooden in the 2010 inaugural draft (Round 7, Pick 22, 202nd overall Pick). |
| Drafted 2B C. Gehringer in the 2010 inaugural draft (Round 8, Pick 9, 219th overall Pick). |
| Drafted MR V. Romo in the 2010 inaugural draft (Round 9, Pick 22, 262nd overall Pick). |
| Drafted 1B T. Tucker in the 2010 inaugural draft (Round 10, Pick 9, 279th overall Pick). |
| Drafted SP M. Wolfgang in the 2010 inaugural draft (Round 11, Pick 22, 322nd overall Pick). |
| Drafted 3B D. Farrell in the 2010 inaugural draft (Round 12, Pick 9, 339th overall Pick). |
| Drafted SP C. Griffith in the 2010 inaugural draft (Round 13, Pick 22, 382nd overall Pick). |
| Drafted CL W. Wyatt in the 2010 inaugural draft (Round 14, Pick 9, 399th overall Pick). |
| Drafted MR F. Arellanes in the 2010 inaugural draft (Round 15, Pick 22, 442nd overall Pick). |
| Drafted MR B. Saberhagen in the 2010 inaugural draft (Round 16, Pick 9, 459th overall Pick). |
| Drafted MR B. Swift in the 2010 inaugural draft (Round 17, Pick 22, 502nd overall Pick). |
| Drafted RF R. Maris in the 2010 inaugural draft (Round 18, Pick 9, 519th overall Pick). |
| Drafted C H. Danning in the 2010 inaugural draft (Round 19, Pick 22, 562nd overall Pick). |
| Drafted RF G. Selkirk in the 2010 inaugural draft (Round 20, Pick 9, 579th overall Pick). |
| Drafted 3B D. Holmes in the 2010 inaugural draft (Round 21, Pick 22, 622nd overall Pick). |
| Drafted LF R. Stephenson in the 2010 inaugural draft (Round 22, Pick 9, 639th overall Pick). |
| Drafted SS J. Sullivan in the 2010 inaugural draft (Round 23, Pick 22, 682nd overall Pick). |
| Drafted LF C. Christensen in the 2010 inaugural draft (Round 24, Pick 9, 699th overall Pick). |
| Drafted SP N. Winters in the 2010 inaugural draft (Round 25, Pick 22, 742nd overall Pick). |
| Drafted 3B P. Whitney in the 2010 inaugural draft (Round 26, Pick 9, 759th overall Pick). |
| Drafted SS H. Long in the 2010 inaugural draft (Round 27, Pick 22, 802nd overall Pick). |
| Drafted SP P. Niekro in the 2010 inaugural draft (Round 28, Pick 9, 819th overall Pick). |
| Drafted MR T. Lyons in the 2010 inaugural draft (Round 29, Pick 22, 862nd overall Pick). |
| Drafted 2B B. Boone in the 2010 inaugural draft (Round 30, Pick 9, 879th overall Pick). |
| Drafted RF B. Jacobson in the 2010 inaugural draft (Round 31, Pick 22, 922nd overall Pick). |
| Drafted C R. Hassey in the 2010 inaugural draft (Round 32, Pick 9, 939th overall Pick). |
| Drafted CF M. Haas in the 2010 inaugural draft (Round 33, Pick 22, 982nd overall Pick). |
| Drafted 1B F. McCormick in the 2010 inaugural draft (Round 34, Pick 9, 999th overall Pick). |
| Drafted SP J. Morris in the 2010 inaugural draft (Round 35, Pick 22, 1042nd overall Pick). |
| Drafted SP G. Derby in the 2010 inaugural draft (Round 36, Pick 9, 1059th overall Pick). |
| Drafted SP T. Larkin in the 2010 inaugural draft (Round 37, Pick 22, 1102nd overall Pick). |
| Drafted LF C. Jamieson in the 2010 inaugural draft (Round 38, Pick 9, 1119th overall Pick). |
| Drafted MR D. Jones in the 2010 inaugural draft (Round 39, Pick 22, 1162nd overall Pick). |
| Drafted LF T. Phillips in the 2010 inaugural draft (Round 40, Pick 9, 1179th overall Pick). |
| Purchased the contract of MR T. Lyons from Triple A East End. |
| Purchased the contract of MR D. Jones from Triple A East End. |
| Purchased the contract of C R. Hassey from Triple A East End. |
| Purchased the contract of 2B H. Long from Triple A East End. |
| Purchased the contract of RF B. Jacobson from Triple A East End. |
| Demoted SP N. Winters to Triple A East End. |
| Demoted 3B D. Farrell to Triple A East End. |
| Demoted C H. Danning to Triple A East End. |
| Demoted SS J. Sullivan to Triple A East End. |
| Demoted LF C. Christensen to Triple A East End. |
