| Friday, January 1st, 2010 |
| Drafted 2B S. White in the 2010 inaugural draft (Round 1, Pick 3, 3rd overall Pick). |
| Drafted RF P. Waner in the 2010 inaugural draft (Round 2, Pick 28, 58th overall Pick). |
| Drafted SS E. Delahanty in the 2010 inaugural draft (Round 3, Pick 3, 63rd overall Pick). |
| Drafted SP H. Camnitz in the 2010 inaugural draft (Round 4, Pick 28, 118th overall Pick). |
| Drafted SP L. Baldwin in the 2010 inaugural draft (Round 5, Pick 3, 123rd overall Pick). |
| Drafted 1B H. Greenberg in the 2010 inaugural draft (Round 6, Pick 28, 178th overall Pick). |
| Drafted SP C. Sweeney in the 2010 inaugural draft (Round 7, Pick 3, 183rd overall Pick). |
| Drafted LF F. Robinson in the 2010 inaugural draft (Round 8, Pick 28, 238th overall Pick). |
| Drafted CF L. Walker in the 2010 inaugural draft (Round 9, Pick 3, 243rd overall Pick). |
| Drafted C M. Grady in the 2010 inaugural draft (Round 10, Pick 28, 298th overall Pick). |
| Drafted SP C. Mays in the 2010 inaugural draft (Round 11, Pick 3, 303rd overall Pick). |
| Drafted MR B. Rhoads in the 2010 inaugural draft (Round 12, Pick 28, 358th overall Pick). |
| Drafted MR J. Brewer in the 2010 inaugural draft (Round 13, Pick 3, 363rd overall Pick). |
| Drafted SP R. Narleski in the 2010 inaugural draft (Round 14, Pick 28, 418th overall Pick). |
| Drafted 3B P. Traynor in the 2010 inaugural draft (Round 15, Pick 3, 423rd overall Pick). |
| Drafted MR W. Twitchell in the 2010 inaugural draft (Round 16, Pick 28, 478th overall Pick). |
| Drafted CL D. Radatz in the 2010 inaugural draft (Round 17, Pick 3, 483rd overall Pick). |
| Drafted C C. Sukeforth in the 2010 inaugural draft (Round 18, Pick 28, 538th overall Pick). |
| Drafted CL J. Hiller in the 2010 inaugural draft (Round 19, Pick 3, 543rd overall Pick). |
| Drafted CL B. Landrum in the 2010 inaugural draft (Round 20, Pick 28, 598th overall Pick). |
| Drafted MR D. Robinson in the 2010 inaugural draft (Round 21, Pick 3, 603rd overall Pick). |
| Drafted CF D. Gladden in the 2010 inaugural draft (Round 22, Pick 28, 658th overall Pick). |
| Drafted SS T. Jackson in the 2010 inaugural draft (Round 23, Pick 3, 663rd overall Pick). |
| Drafted SP M. Russo in the 2010 inaugural draft (Round 24, Pick 28, 718th overall Pick). |
| Drafted SP C. Lundgren in the 2010 inaugural draft (Round 25, Pick 3, 723rd overall Pick). |
| Drafted LF C. Jones in the 2010 inaugural draft (Round 26, Pick 28, 778th overall Pick). |
| Drafted 2B L. Magee in the 2010 inaugural draft (Round 27, Pick 3, 783rd overall Pick). |
| Drafted MR C. Fraser in the 2010 inaugural draft (Round 28, Pick 28, 838th overall Pick). |
| Drafted CF G. Harper in the 2010 inaugural draft (Round 29, Pick 3, 843rd overall Pick). |
| Drafted 3B T. Pendleton in the 2010 inaugural draft (Round 30, Pick 28, 898th overall Pick). |
| Drafted C S. O'Neill in the 2010 inaugural draft (Round 31, Pick 3, 903rd overall Pick). |
| Drafted SP B. Walters in the 2010 inaugural draft (Round 32, Pick 28, 958th overall Pick). |
| Drafted SP B. Hutchison in the 2010 inaugural draft (Round 33, Pick 3, 963rd overall Pick). |
| Drafted SS D. Farrell in the 2010 inaugural draft (Round 34, Pick 28, 1018th overall Pick). |
| Drafted RF S. Seybold in the 2010 inaugural draft (Round 35, Pick 3, 1023rd overall Pick). |
| Drafted SP P. Hawley in the 2010 inaugural draft (Round 36, Pick 28, 1078th overall Pick). |
| Drafted 1B D. Burrus in the 2010 inaugural draft (Round 37, Pick 3, 1083rd overall Pick). |
| Drafted MR K. Saucier in the 2010 inaugural draft (Round 38, Pick 28, 1138th overall Pick). |
| Drafted CL J. Grzenda in the 2010 inaugural draft (Round 39, Pick 3, 1143rd overall Pick). |
| Drafted 2B M. Stock in the 2010 inaugural draft (Round 40, Pick 28, 1198th overall Pick). |
| Drafted SS D. Concepcion in the 2010 inaugural draft (Round 41, Pick 3, 1203rd overall Pick). |
| Purchased the contract of CL J. Grzenda from Triple A River Oaks. |
| Purchased the contract of MR C. Fraser from Triple A River Oaks. |
| Purchased the contract of CF G. Harper from Triple A River Oaks. |
| Purchased the contract of LF C. Jones from Triple A River Oaks. |
| Demoted SP M. Russo to Triple A River Oaks. |
| Demoted CL D. Radatz to Triple A River Oaks. |
| Demoted MR D. Robinson to Triple A River Oaks. |
| Demoted CL B. Landrum to Triple A River Oaks. |
| Demoted 2B M. Stock from Triple A River Oaks to Double A Minneapolis. |
| Demoted SS D. Farrell from Triple A River Oaks to Double A Minneapolis. |
