| Friday, January 1st, 2010 |
| Drafted LF B. Ruth in the 2010 inaugural draft (Round 1, Pick 10, 10th overall Pick). |
| Drafted 1B G. Sisler in the 2010 inaugural draft (Round 2, Pick 21, 51st overall Pick). |
| Drafted RF P. Waner in the 2010 inaugural draft (Round 3, Pick 10, 70th overall Pick). |
| Drafted SP J. Pfiester in the 2010 inaugural draft (Round 4, Pick 21, 111st overall Pick). |
| Drafted SP S. Chandler in the 2010 inaugural draft (Round 5, Pick 10, 130th overall Pick). |
| Drafted SP C. Sweeney in the 2010 inaugural draft (Round 6, Pick 21, 171st overall Pick). |
| Drafted C J. Milligan in the 2010 inaugural draft (Round 7, Pick 10, 190th overall Pick). |
| Drafted 2B J. Robinson in the 2010 inaugural draft (Round 8, Pick 21, 231st overall Pick). |
| Drafted SP C. Griffith in the 2010 inaugural draft (Round 9, Pick 10, 250th overall Pick). |
| Drafted MR D. Ellsworth in the 2010 inaugural draft (Round 10, Pick 21, 291st overall Pick). |
| Drafted 3B P. Higgins in the 2010 inaugural draft (Round 11, Pick 10, 310th overall Pick). |
| Drafted CL G. Olson in the 2010 inaugural draft (Round 12, Pick 21, 351st overall Pick). |
| Drafted SP H. Smith in the 2010 inaugural draft (Round 13, Pick 10, 370th overall Pick). |
| Drafted SS L. Appling in the 2010 inaugural draft (Round 14, Pick 21, 411st overall Pick). |
| Drafted CF T. Speaker in the 2010 inaugural draft (Round 15, Pick 10, 430th overall Pick). |
| Drafted MR W. Twitchell in the 2010 inaugural draft (Round 16, Pick 21, 471st overall Pick). |
| Drafted MR D. Veres in the 2010 inaugural draft (Round 17, Pick 10, 490th overall Pick). |
| Drafted MR A. Brazle in the 2010 inaugural draft (Round 18, Pick 21, 531st overall Pick). |
| Drafted C C. Sukeforth in the 2010 inaugural draft (Round 19, Pick 10, 550th overall Pick). |
| Drafted LF R. Henderson in the 2010 inaugural draft (Round 20, Pick 21, 591st overall Pick). |
| Drafted DH R. Jefferson in the 2010 inaugural draft (Round 21, Pick 10, 610th overall Pick). |
| Drafted RF D. Parker in the 2010 inaugural draft (Round 22, Pick 21, 651st overall Pick). |
| Drafted 1B D. Brouthers in the 2010 inaugural draft (Round 23, Pick 10, 670th overall Pick). |
| Drafted SP O. Overall in the 2010 inaugural draft (Round 24, Pick 21, 711st overall Pick). |
| Drafted SP L. Cadore in the 2010 inaugural draft (Round 25, Pick 10, 730th overall Pick). |
| Drafted SP N. Altrock in the 2010 inaugural draft (Round 26, Pick 21, 771st overall Pick). |
| Drafted 1B Z. Bonura in the 2010 inaugural draft (Round 27, Pick 10, 790th overall Pick). |
| Drafted 2B L. Magee in the 2010 inaugural draft (Round 28, Pick 21, 831st overall Pick). |
| Drafted RF C. Williams in the 2010 inaugural draft (Round 29, Pick 10, 850th overall Pick). |
| Drafted SP J. Niggeling in the 2010 inaugural draft (Round 30, Pick 21, 891st overall Pick). |
| Drafted CF M. Haas in the 2010 inaugural draft (Round 31, Pick 10, 910th overall Pick). |
| Drafted SS A. Dark in the 2010 inaugural draft (Round 32, Pick 21, 951st overall Pick). |
| Drafted C M. Sanguillen in the 2010 inaugural draft (Round 33, Pick 10, 970th overall Pick). |
| Drafted SP H. Aguirre in the 2010 inaugural draft (Round 34, Pick 21, 1011st overall Pick). |
| Drafted MR E. Watt in the 2010 inaugural draft (Round 35, Pick 10, 1030th overall Pick). |
| Drafted CL J. Hoerner in the 2010 inaugural draft (Round 36, Pick 21, 1071st overall Pick). |
| Drafted SP N. Ryan in the 2010 inaugural draft (Round 37, Pick 10, 1090th overall Pick). |
| Drafted MR M. Brown in the 2010 inaugural draft (Round 38, Pick 21, 1131st overall Pick). |
| Drafted 3B R. Rolfe in the 2010 inaugural draft (Round 39, Pick 10, 1150th overall Pick). |
| Drafted LF R. Radcliff in the 2010 inaugural draft (Round 40, Pick 21, 1191st overall Pick). |
