| Friday, January 1st, 2010 |
| Drafted 1B B. Taylor in the 2010 inaugural draft (Round 1, Pick 23, 23rd overall Pick). |
| Drafted 2B R. Hornsby in the 2010 inaugural draft (Round 2, Pick 8, 38th overall Pick). |
| Drafted LF J. Medwick in the 2010 inaugural draft (Round 3, Pick 23, 83rd overall Pick). |
| Drafted SP T. McGraw in the 2010 inaugural draft (Round 4, Pick 8, 98th overall Pick). |
| Drafted SP D. Rudolph in the 2010 inaugural draft (Round 5, Pick 23, 143rd overall Pick). |
| Drafted C G. Mancuso in the 2010 inaugural draft (Round 6, Pick 8, 158th overall Pick). |
| Drafted SP D. McNally in the 2010 inaugural draft (Round 7, Pick 23, 203rd overall Pick). |
| Drafted 3B M. Schmidt in the 2010 inaugural draft (Round 8, Pick 8, 218th overall Pick). |
| Drafted CL D. Vance in the 2010 inaugural draft (Round 9, Pick 23, 263rd overall Pick). |
| Drafted SP E. Karger in the 2010 inaugural draft (Round 10, Pick 8, 278th overall Pick). |
| Drafted SP M. Wolfgang in the 2010 inaugural draft (Round 11, Pick 23, 323rd overall Pick). |
| Drafted RF G. Goslin in the 2010 inaugural draft (Round 12, Pick 8, 338th overall Pick). |
| Drafted CF B. Anderson in the 2010 inaugural draft (Round 13, Pick 23, 383rd overall Pick). |
| Drafted SS E. McKean in the 2010 inaugural draft (Round 14, Pick 8, 398th overall Pick). |
| Drafted MR L. McDaniel in the 2010 inaugural draft (Round 15, Pick 23, 443rd overall Pick). |
| Drafted MR T. Seaver in the 2010 inaugural draft (Round 16, Pick 8, 458th overall Pick). |
| Drafted MR S. Perry in the 2010 inaugural draft (Round 17, Pick 23, 503rd overall Pick). |
| Drafted C J. Lapp in the 2010 inaugural draft (Round 18, Pick 8, 518th overall Pick). |
| Drafted MR J. Acker in the 2010 inaugural draft (Round 19, Pick 23, 563rd overall Pick). |
| Drafted RF B. Campbell in the 2010 inaugural draft (Round 20, Pick 8, 578th overall Pick). |
| Drafted LF G. Hall in the 2010 inaugural draft (Round 21, Pick 23, 623rd overall Pick). |
| Drafted LF J. Vosmik in the 2010 inaugural draft (Round 22, Pick 8, 638th overall Pick). |
| Drafted LF H. Manush in the 2010 inaugural draft (Round 23, Pick 23, 683rd overall Pick). |
| Drafted SP B. Emslie in the 2010 inaugural draft (Round 24, Pick 8, 698th overall Pick). |
| Drafted SP W. Bunker in the 2010 inaugural draft (Round 25, Pick 23, 743rd overall Pick). |
| Drafted SP H. Wiltse in the 2010 inaugural draft (Round 26, Pick 8, 758th overall Pick). |
| Drafted 1B J. Beckley in the 2010 inaugural draft (Round 27, Pick 23, 803rd overall Pick). |
| Drafted SS H. Long in the 2010 inaugural draft (Round 28, Pick 8, 818th overall Pick). |
| Drafted 3B B. Madlock in the 2010 inaugural draft (Round 29, Pick 23, 863rd overall Pick). |
| Drafted SP G. Jackson in the 2010 inaugural draft (Round 30, Pick 8, 878th overall Pick). |
| Drafted LF P. Cavarretta in the 2010 inaugural draft (Round 31, Pick 23, 923rd overall Pick). |
| Drafted CL J. Aker in the 2010 inaugural draft (Round 32, Pick 8, 938th overall Pick). |
| Drafted RF T. Brown in the 2010 inaugural draft (Round 33, Pick 23, 983rd overall Pick). |
| Drafted MR J. Franco in the 2010 inaugural draft (Round 34, Pick 8, 998th overall Pick). |
| Drafted 2B C. Biggio in the 2010 inaugural draft (Round 35, Pick 23, 1043rd overall Pick). |
| Drafted SP T. Hughes in the 2010 inaugural draft (Round 36, Pick 8, 1058th overall Pick). |
| Drafted SP T. Larkin in the 2010 inaugural draft (Round 37, Pick 23, 1103rd overall Pick). |
| Drafted SP J. Denny in the 2010 inaugural draft (Round 38, Pick 8, 1118th overall Pick). |
| Drafted 1B J. Delahanty in the 2010 inaugural draft (Round 39, Pick 23, 1163rd overall Pick). |
| Drafted 1B G. Burns in the 2010 inaugural draft (Round 40, Pick 8, 1178th overall Pick). |
