| Friday, January 1st, 2010 |
| Drafted RF E. Flick in the 2010 inaugural draft (Round 1, Pick 20, 20th overall Pick). |
| Drafted 3B G. Brett in the 2010 inaugural draft (Round 2, Pick 11, 41st overall Pick). |
| Drafted SS J. Cronin in the 2010 inaugural draft (Round 3, Pick 20, 80th overall Pick). |
| Drafted SP C. Fisher in the 2010 inaugural draft (Round 4, Pick 11, 101st overall Pick). |
| Drafted SP M. Brown in the 2010 inaugural draft (Round 5, Pick 20, 140th overall Pick). |
| Drafted C E. Bailey in the 2010 inaugural draft (Round 6, Pick 11, 161st overall Pick). |
| Drafted SP G. Maddux in the 2010 inaugural draft (Round 7, Pick 20, 200th overall Pick). |
| Drafted 2B C. Gehringer in the 2010 inaugural draft (Round 8, Pick 11, 221st overall Pick). |
| Drafted MR J. Brewer in the 2010 inaugural draft (Round 9, Pick 20, 260th overall Pick). |
| Drafted 1B H. Killebrew in the 2010 inaugural draft (Round 10, Pick 11, 281st overall Pick). |
| Drafted LF T. Francona in the 2010 inaugural draft (Round 11, Pick 20, 320th overall Pick). |
| Drafted CF B. Holliday in the 2010 inaugural draft (Round 12, Pick 11, 341st overall Pick). |
| Drafted SP M. Cooper in the 2010 inaugural draft (Round 13, Pick 20, 380th overall Pick). |
| Drafted MR C. Schilling in the 2010 inaugural draft (Round 14, Pick 11, 401st overall Pick). |
| Drafted MR R. Vickers in the 2010 inaugural draft (Round 15, Pick 20, 440th overall Pick). |
| Drafted SP R. Munger in the 2010 inaugural draft (Round 16, Pick 11, 461st overall Pick). |
| Drafted MR T. Burgmeier in the 2010 inaugural draft (Round 17, Pick 20, 500th overall Pick). |
| Drafted C G. Myatt in the 2010 inaugural draft (Round 18, Pick 11, 521st overall Pick). |
| Drafted MR D. Foutz in the 2010 inaugural draft (Round 19, Pick 20, 560th overall Pick). |
| Drafted RF J. Rice in the 2010 inaugural draft (Round 20, Pick 11, 581st overall Pick). |
| Drafted SS G. Wright in the 2010 inaugural draft (Round 21, Pick 20, 620th overall Pick). |
| Drafted RF D. Bichette in the 2010 inaugural draft (Round 22, Pick 11, 641st overall Pick). |
| Drafted RF P. Fox in the 2010 inaugural draft (Round 23, Pick 20, 680th overall Pick). |
| Drafted SS J. Harris in the 2010 inaugural draft (Round 24, Pick 11, 701st overall Pick). |
| Drafted SS K. Elberfeld in the 2010 inaugural draft (Round 25, Pick 20, 740th overall Pick). |
| Drafted LF C. Christensen in the 2010 inaugural draft (Round 26, Pick 11, 761st overall Pick). |
| Drafted CF B. Jackson in the 2010 inaugural draft (Round 27, Pick 20, 800th overall Pick). |
| Drafted RF G. Case in the 2010 inaugural draft (Round 28, Pick 11, 821st overall Pick). |
| Drafted C C. Anson in the 2010 inaugural draft (Round 29, Pick 20, 860th overall Pick). |
| Drafted SP D. Martinez in the 2010 inaugural draft (Round 30, Pick 11, 881st overall Pick). |
| Drafted MR M. Wohlers in the 2010 inaugural draft (Round 31, Pick 20, 920th overall Pick). |
| Drafted SS J. Denny in the 2010 inaugural draft (Round 32, Pick 11, 941st overall Pick). |
| Drafted MR E. Willett in the 2010 inaugural draft (Round 33, Pick 20, 980th overall Pick). |
| Drafted MR W. Brusstar in the 2010 inaugural draft (Round 34, Pick 11, 1001st overall Pick). |
| Drafted SP J. Kaat in the 2010 inaugural draft (Round 35, Pick 20, 1040th overall Pick). |
| Drafted SP J. Morris in the 2010 inaugural draft (Round 36, Pick 11, 1061st overall Pick). |
| Drafted CL J. Grzenda in the 2010 inaugural draft (Round 37, Pick 20, 1100th overall Pick). |
| Drafted 2B W. Fisler in the 2010 inaugural draft (Round 38, Pick 11, 1121st overall Pick). |
| Drafted 3B B. Weaver in the 2010 inaugural draft (Round 39, Pick 20, 1160th overall Pick). |
| Drafted SS D. Pratt in the 2010 inaugural draft (Round 40, Pick 11, 1181st overall Pick). |
