| Friday, January 1st, 2010 |
| Drafted 1B L. Gehrig in the 2010 inaugural draft (Round 1, Pick 5, 5th overall Pick). |
| Drafted CF S. Musial in the 2010 inaugural draft (Round 2, Pick 26, 56th overall Pick). |
| Drafted LF D. Rhodes in the 2010 inaugural draft (Round 3, Pick 5, 65th overall Pick). |
| Drafted SP B. Bernhard in the 2010 inaugural draft (Round 4, Pick 26, 116th overall Pick). |
| Drafted SP E. Cicotte in the 2010 inaugural draft (Round 5, Pick 5, 125th overall Pick). |
| Drafted C J. Milligan in the 2010 inaugural draft (Round 6, Pick 26, 176th overall Pick). |
| Drafted SP J. Clarkson in the 2010 inaugural draft (Round 7, Pick 5, 185th overall Pick). |
| Drafted RF S. Sosa in the 2010 inaugural draft (Round 8, Pick 26, 236th overall Pick). |
| Drafted 2B G. Watkins in the 2010 inaugural draft (Round 9, Pick 5, 245th overall Pick). |
| Drafted MR E. Moore in the 2010 inaugural draft (Round 10, Pick 26, 296th overall Pick). |
| Drafted SS E. Banks in the 2010 inaugural draft (Round 11, Pick 5, 305th overall Pick). |
| Drafted 3B B. Bailey in the 2010 inaugural draft (Round 12, Pick 26, 356th overall Pick). |
| Drafted SP R. Clemens in the 2010 inaugural draft (Round 13, Pick 5, 365th overall Pick). |
| Drafted CL K. Tekulve in the 2010 inaugural draft (Round 14, Pick 26, 416th overall Pick). |
| Drafted MR B. Friend in the 2010 inaugural draft (Round 15, Pick 5, 425th overall Pick). |
| Drafted CL R. Camp in the 2010 inaugural draft (Round 16, Pick 26, 476th overall Pick). |
| Drafted SP E. Summers in the 2010 inaugural draft (Round 17, Pick 5, 485th overall Pick). |
| Drafted MR K. Forsch in the 2010 inaugural draft (Round 18, Pick 26, 536th overall Pick). |
| Drafted MR C. Morgan in the 2010 inaugural draft (Round 19, Pick 5, 545th overall Pick). |
| Drafted C E. Brucker in the 2010 inaugural draft (Round 20, Pick 26, 596th overall Pick). |
| Drafted RF C. Yastrzemski in the 2010 inaugural draft (Round 21, Pick 5, 605th overall Pick). |
| Drafted SP E. Siever in the 2010 inaugural draft (Round 22, Pick 26, 656th overall Pick). |
| Drafted SP A. Coakley in the 2010 inaugural draft (Round 23, Pick 5, 665th overall Pick). |
| Drafted SP G. Mogridge in the 2010 inaugural draft (Round 24, Pick 26, 716th overall Pick). |
| Drafted SP P. Jarvis in the 2010 inaugural draft (Round 25, Pick 5, 725th overall Pick). |
| Drafted SP S. Barber in the 2010 inaugural draft (Round 26, Pick 26, 776th overall Pick). |
| Drafted LF R. Blades in the 2010 inaugural draft (Round 27, Pick 5, 785th overall Pick). |
| Drafted CL B. Landrum in the 2010 inaugural draft (Round 28, Pick 26, 836th overall Pick). |
| Drafted CF G. Harper in the 2010 inaugural draft (Round 29, Pick 5, 845th overall Pick). |
| Drafted SP W. Spahn in the 2010 inaugural draft (Round 30, Pick 26, 896th overall Pick). |
| Drafted C B. Harper in the 2010 inaugural draft (Round 31, Pick 5, 905th overall Pick). |
| Drafted 2B P. Lloyd in the 2010 inaugural draft (Round 32, Pick 26, 956th overall Pick). |
| Drafted SP K. Brown in the 2010 inaugural draft (Round 33, Pick 5, 965th overall Pick). |
| Drafted RF D. Mueller in the 2010 inaugural draft (Round 34, Pick 26, 1016th overall Pick). |
| Drafted SP J. Kaat in the 2010 inaugural draft (Round 35, Pick 5, 1025th overall Pick). |
| Drafted 1B M. Grace in the 2010 inaugural draft (Round 36, Pick 26, 1076th overall Pick). |
| Drafted SP N. Ryan in the 2010 inaugural draft (Round 37, Pick 5, 1085th overall Pick). |
| Drafted 3B R. Rolfe in the 2010 inaugural draft (Round 38, Pick 26, 1136th overall Pick). |
| Drafted SS B. Friberg in the 2010 inaugural draft (Round 39, Pick 5, 1145th overall Pick). |
| Drafted 1B B. Robinson in the 2010 inaugural draft (Round 40, Pick 26, 1196th overall Pick). |
