| Friday, January 1st, 2010 |
| Drafted LF B. Ruth in the 2010 inaugural draft (Round 1, Pick 10, 10th overall Pick). |
| Drafted 1B G. Sisler in the 2010 inaugural draft (Round 2, Pick 21, 51st overall Pick). |
| Drafted SS J. McGraw in the 2010 inaugural draft (Round 3, Pick 10, 70th overall Pick). |
| Drafted SP R. Gossage in the 2010 inaugural draft (Round 4, Pick 21, 111st overall Pick). |
| Drafted SP J. Williams in the 2010 inaugural draft (Round 5, Pick 10, 130th overall Pick). |
| Drafted RF R. Fairly in the 2010 inaugural draft (Round 6, Pick 21, 171st overall Pick). |
| Drafted SP F. Goldsmith in the 2010 inaugural draft (Round 7, Pick 10, 190th overall Pick). |
| Drafted 3B M. Schmidt in the 2010 inaugural draft (Round 8, Pick 21, 231st overall Pick). |
| Drafted MR J. Brewer in the 2010 inaugural draft (Round 9, Pick 10, 250th overall Pick). |
| Drafted C S. Burgess in the 2010 inaugural draft (Round 10, Pick 21, 291st overall Pick). |
| Drafted CF S. Brodie in the 2010 inaugural draft (Round 11, Pick 10, 310th overall Pick). |
| Drafted 2B S. Sax in the 2010 inaugural draft (Round 12, Pick 21, 351st overall Pick). |
| Drafted SP M. Cooper in the 2010 inaugural draft (Round 13, Pick 10, 370th overall Pick). |
| Drafted MR H. Brecheen in the 2010 inaugural draft (Round 14, Pick 21, 411st overall Pick). |
| Drafted SP G. Zettlein in the 2010 inaugural draft (Round 15, Pick 10, 430th overall Pick). |
| Drafted MR B. Dineen in the 2010 inaugural draft (Round 16, Pick 21, 471st overall Pick). |
| Drafted MR A. Demaree in the 2010 inaugural draft (Round 17, Pick 10, 490th overall Pick). |
| Drafted MR B. Swift in the 2010 inaugural draft (Round 18, Pick 21, 531st overall Pick). |
| Drafted C B. Downing in the 2010 inaugural draft (Round 19, Pick 10, 550th overall Pick). |
| Drafted RF B. Campbell in the 2010 inaugural draft (Round 20, Pick 21, 591st overall Pick). |
| Drafted CF C. Seymour in the 2010 inaugural draft (Round 21, Pick 10, 610th overall Pick). |
| Drafted LF B. Allison in the 2010 inaugural draft (Round 22, Pick 21, 651st overall Pick). |
| Drafted LF K. Selbach in the 2010 inaugural draft (Round 23, Pick 10, 670th overall Pick). |
| Drafted 2B B. Sweeney in the 2010 inaugural draft (Round 24, Pick 21, 711st overall Pick). |
| Drafted 2B S. Stirnweiss in the 2010 inaugural draft (Round 25, Pick 10, 730th overall Pick). |
| Drafted SS A. Fletcher in the 2010 inaugural draft (Round 26, Pick 21, 771st overall Pick). |
| Drafted 3B J. Collins in the 2010 inaugural draft (Round 27, Pick 10, 790th overall Pick). |
| Drafted SP W. Wood in the 2010 inaugural draft (Round 28, Pick 21, 831st overall Pick). |
| Drafted RF C. Williams in the 2010 inaugural draft (Round 29, Pick 10, 850th overall Pick). |
| Drafted 2B B. Myer in the 2010 inaugural draft (Round 30, Pick 21, 891st overall Pick). |
| Drafted MR D. Ruether in the 2010 inaugural draft (Round 31, Pick 10, 910th overall Pick). |
| Drafted LF E. Combs in the 2010 inaugural draft (Round 32, Pick 21, 951st overall Pick). |
| Drafted MR B. Reynolds in the 2010 inaugural draft (Round 33, Pick 10, 970th overall Pick). |
| Drafted MR J. Franco in the 2010 inaugural draft (Round 34, Pick 21, 1011st overall Pick). |
| Drafted MR S. Lyle in the 2010 inaugural draft (Round 35, Pick 10, 1030th overall Pick). |
| Drafted CL J. Konstanty in the 2010 inaugural draft (Round 36, Pick 21, 1071st overall Pick). |
| Drafted C H. Gowdy in the 2010 inaugural draft (Round 37, Pick 10, 1090th overall Pick). |
| Drafted 1B D. Orr in the 2010 inaugural draft (Round 38, Pick 21, 1131st overall Pick). |
| Drafted 2B E. Stanky in the 2010 inaugural draft (Round 39, Pick 10, 1150th overall Pick). |
| Drafted RF S. Rice in the 2010 inaugural draft (Round 40, Pick 21, 1191st overall Pick). |
