| Friday, January 1st, 2010 |
| Drafted 2B S. White in the 2010 inaugural draft (Round 1, Pick 3, 3rd overall Pick). |
| Drafted RF H. Baines in the 2010 inaugural draft (Round 2, Pick 28, 58th overall Pick). |
| Drafted LF T. Conigliaro in the 2010 inaugural draft (Round 3, Pick 3, 63rd overall Pick). |
| Drafted SP P. Werden in the 2010 inaugural draft (Round 4, Pick 28, 118th overall Pick). |
| Drafted SP B. Rhines in the 2010 inaugural draft (Round 5, Pick 3, 123rd overall Pick). |
| Drafted C N. Clarke in the 2010 inaugural draft (Round 6, Pick 28, 178th overall Pick). |
| Drafted SP D. Burns in the 2010 inaugural draft (Round 7, Pick 3, 183rd overall Pick). |
| Drafted MR T. Niedenfuer in the 2010 inaugural draft (Round 8, Pick 28, 238th overall Pick). |
| Drafted 1B H. Greenberg in the 2010 inaugural draft (Round 9, Pick 3, 243rd overall Pick). |
| Drafted 3B R. Santo in the 2010 inaugural draft (Round 10, Pick 28, 298th overall Pick). |
| Drafted SP N. Maddox in the 2010 inaugural draft (Round 11, Pick 3, 303rd overall Pick). |
| Drafted SP M. Fidrych in the 2010 inaugural draft (Round 12, Pick 28, 358th overall Pick). |
| Drafted SS H. Johnson in the 2010 inaugural draft (Round 13, Pick 3, 363rd overall Pick). |
| Drafted CF B. Anderson in the 2010 inaugural draft (Round 14, Pick 28, 418th overall Pick). |
| Drafted MR O. Hess in the 2010 inaugural draft (Round 15, Pick 3, 423rd overall Pick). |
| Drafted MR B. Lee in the 2010 inaugural draft (Round 16, Pick 28, 478th overall Pick). |
| Drafted CL D. Radatz in the 2010 inaugural draft (Round 17, Pick 3, 483rd overall Pick). |
| Drafted C J. Grim in the 2010 inaugural draft (Round 18, Pick 28, 538th overall Pick). |
| Drafted CL M. Schooler in the 2010 inaugural draft (Round 19, Pick 3, 543rd overall Pick). |
| Drafted MR E. Hamilton in the 2010 inaugural draft (Round 20, Pick 28, 598th overall Pick). |
| Drafted LF B. Goodman in the 2010 inaugural draft (Round 21, Pick 3, 603rd overall Pick). |
| Drafted 1B D. Brouthers in the 2010 inaugural draft (Round 22, Pick 28, 658th overall Pick). |
| Drafted LF B. Twombly in the 2010 inaugural draft (Round 23, Pick 3, 663rd overall Pick). |
| Drafted 2B M. McManus in the 2010 inaugural draft (Round 24, Pick 28, 718th overall Pick). |
| Drafted LF A. McHenry in the 2010 inaugural draft (Round 25, Pick 3, 723rd overall Pick). |
| Drafted LF L. Bostock in the 2010 inaugural draft (Round 26, Pick 28, 778th overall Pick). |
| Drafted CF B. Jackson in the 2010 inaugural draft (Round 27, Pick 3, 783rd overall Pick). |
| Drafted MR B. Sutter in the 2010 inaugural draft (Round 28, Pick 28, 838th overall Pick). |
| Drafted SS D. Decinces in the 2010 inaugural draft (Round 29, Pick 3, 843rd overall Pick). |
| Drafted 2B G. Grantham in the 2010 inaugural draft (Round 30, Pick 28, 898th overall Pick). |
| Drafted RF I. Meusel in the 2010 inaugural draft (Round 31, Pick 3, 903rd overall Pick). |
| Drafted SP M. Mussina in the 2010 inaugural draft (Round 32, Pick 28, 958th overall Pick). |
| Drafted C R. Schalk in the 2010 inaugural draft (Round 33, Pick 3, 963rd overall Pick). |
| Drafted SP E. Moseley in the 2010 inaugural draft (Round 34, Pick 28, 1018th overall Pick). |
| Drafted SP F. Bradley in the 2010 inaugural draft (Round 35, Pick 3, 1023rd overall Pick). |
| Drafted 1B G. Kelly in the 2010 inaugural draft (Round 36, Pick 28, 1078th overall Pick). |
| Drafted 3B H. Groh in the 2010 inaugural draft (Round 37, Pick 3, 1083rd overall Pick). |
| Drafted 1B F. Alou in the 2010 inaugural draft (Round 38, Pick 28, 1138th overall Pick). |
| Drafted RF A. Galan in the 2010 inaugural draft (Round 39, Pick 3, 1143rd overall Pick). |
| Drafted 2B M. Stock in the 2010 inaugural draft (Round 40, Pick 28, 1198th overall Pick). |
