| Friday, January 1st, 2010 |
| Drafted CF M. Mantle in the 2010 inaugural draft (Round 1, Pick 6, 6th overall Pick). |
| Drafted 1B M. Suttles in the 2010 inaugural draft (Round 2, Pick 25, 55th overall Pick). |
| Drafted 3B D. Allen in the 2010 inaugural draft (Round 3, Pick 6, 66th overall Pick). |
| Drafted SP J. Pfiester in the 2010 inaugural draft (Round 4, Pick 25, 115th overall Pick). |
| Drafted SP R. Nelson in the 2010 inaugural draft (Round 5, Pick 6, 126th overall Pick). |
| Drafted SP C. Ferguson in the 2010 inaugural draft (Round 6, Pick 25, 175th overall Pick). |
| Drafted RF J. Gonzalez in the 2010 inaugural draft (Round 7, Pick 6, 186th overall Pick). |
| Drafted CL W. Hernandez in the 2010 inaugural draft (Round 8, Pick 25, 235th overall Pick). |
| Drafted C J. Lopez in the 2010 inaugural draft (Round 9, Pick 6, 246th overall Pick). |
| Drafted SP H. Berger in the 2010 inaugural draft (Round 10, Pick 25, 295th overall Pick). |
| Drafted MR D. Ellsworth in the 2010 inaugural draft (Round 11, Pick 6, 306th overall Pick). |
| Drafted LF T. Francona in the 2010 inaugural draft (Round 12, Pick 25, 355th overall Pick). |
| Drafted 2B R. Wrightstone in the 2010 inaugural draft (Round 13, Pick 6, 366th overall Pick). |
| Drafted SP R. Narleski in the 2010 inaugural draft (Round 14, Pick 25, 415th overall Pick). |
| Drafted MR C. Chech in the 2010 inaugural draft (Round 15, Pick 6, 426th overall Pick). |
| Drafted SS J. Valentin in the 2010 inaugural draft (Round 16, Pick 25, 475th overall Pick). |
| Drafted MR G. Minton in the 2010 inaugural draft (Round 17, Pick 6, 486th overall Pick). |
| Drafted C B. Henline in the 2010 inaugural draft (Round 18, Pick 25, 535th overall Pick). |
| Drafted CL R. Perranoski in the 2010 inaugural draft (Round 19, Pick 6, 546th overall Pick). |
| Drafted CL B. Adams in the 2010 inaugural draft (Round 20, Pick 25, 595th overall Pick). |
| Drafted MR P. Richert in the 2010 inaugural draft (Round 21, Pick 6, 606th overall Pick). |
| Drafted RF J. Heath in the 2010 inaugural draft (Round 22, Pick 25, 655th overall Pick). |
| Drafted LF M. Rettenmund in the 2010 inaugural draft (Round 23, Pick 6, 666th overall Pick). |
| Drafted SP C. Lundgren in the 2010 inaugural draft (Round 24, Pick 25, 715th overall Pick). |
| Drafted LF B. Miller in the 2010 inaugural draft (Round 25, Pick 6, 726th overall Pick). |
| Drafted SP D. Gullett in the 2010 inaugural draft (Round 26, Pick 25, 775th overall Pick). |
| Drafted CF B. Williams in the 2010 inaugural draft (Round 27, Pick 6, 786th overall Pick). |
| Drafted C W. Cooper in the 2010 inaugural draft (Round 28, Pick 25, 835th overall Pick). |
| Drafted 3B B. Elliott in the 2010 inaugural draft (Round 29, Pick 6, 846th overall Pick). |
| Drafted LF B. Williams in the 2010 inaugural draft (Round 30, Pick 25, 895th overall Pick). |
| Drafted 1B T. Martinez in the 2010 inaugural draft (Round 31, Pick 6, 906th overall Pick). |
| Drafted 2B F. Vina in the 2010 inaugural draft (Round 32, Pick 25, 955th overall Pick). |
| Drafted RF T. Oliva in the 2010 inaugural draft (Round 33, Pick 6, 966th overall Pick). |
| Drafted MR W. Brusstar in the 2010 inaugural draft (Round 34, Pick 25, 1015th overall Pick). |
| Drafted SS H. Richardson in the 2010 inaugural draft (Round 35, Pick 6, 1026th overall Pick). |
| Drafted CL R. Hernandez in the 2010 inaugural draft (Round 36, Pick 25, 1075th overall Pick). |
| Drafted CL R. Nen in the 2010 inaugural draft (Round 37, Pick 6, 1086th overall Pick). |
| Drafted DH R. Kittle in the 2010 inaugural draft (Round 38, Pick 25, 1135th overall Pick). |
| Drafted LF F. Howard in the 2010 inaugural draft (Round 39, Pick 6, 1146th overall Pick). |
| Drafted RF H. Hooper in the 2010 inaugural draft (Round 40, Pick 25, 1195th overall Pick). |
