| Friday, January 1st, 2010 |
| Drafted CF B. Lange in the 2010 inaugural draft (Round 1, Pick 28, 28th overall Pick). |
| Drafted C B. Petway in the 2010 inaugural draft (Round 2, Pick 17, 47th overall Pick). |
| Drafted SS N. Lajoie in the 2010 inaugural draft (Round 3, Pick 14, 74th overall Pick). |
| Drafted SP C. Mathewson in the 2010 inaugural draft (Round 4, Pick 17, 107th overall Pick). |
| Drafted SP J. McGinnity in the 2010 inaugural draft (Round 5, Pick 14, 134th overall Pick). |
| Drafted SP D. Gooden in the 2010 inaugural draft (Round 6, Pick 17, 167th overall Pick). |
| Drafted SP L. Richmond in the 2010 inaugural draft (Round 7, Pick 14, 194th overall Pick). |
| Drafted MR S. Rowe in the 2010 inaugural draft (Round 8, Pick 17, 227th overall Pick). |
| Drafted LF K. Williams in the 2010 inaugural draft (Round 9, Pick 14, 254th overall Pick). |
| Drafted 1B H. Killebrew in the 2010 inaugural draft (Round 10, Pick 17, 287th overall Pick). |
| Drafted CL A. Fromme in the 2010 inaugural draft (Round 11, Pick 14, 314th overall Pick). |
| Drafted 2B C. Knoblauch in the 2010 inaugural draft (Round 12, Pick 17, 347th overall Pick). |
| Drafted RF S. Thompson in the 2010 inaugural draft (Round 13, Pick 14, 374th overall Pick). |
| Drafted 3B P. Traynor in the 2010 inaugural draft (Round 14, Pick 17, 407th overall Pick). |
| Drafted MR J. Marichal in the 2010 inaugural draft (Round 15, Pick 14, 434th overall Pick). |
| Drafted SP J. Magrane in the 2010 inaugural draft (Round 16, Pick 17, 467th overall Pick). |
| Drafted CL P. Regan in the 2010 inaugural draft (Round 17, Pick 14, 494th overall Pick). |
| Drafted C M. Tettleton in the 2010 inaugural draft (Round 18, Pick 17, 527th overall Pick). |
| Drafted MR D. McMahon in the 2010 inaugural draft (Round 19, Pick 14, 554th overall Pick). |
| Drafted MR G. Garber in the 2010 inaugural draft (Round 20, Pick 17, 587th overall Pick). |
| Drafted LF T. O'Neill in the 2010 inaugural draft (Round 21, Pick 14, 614th overall Pick). |
| Drafted CF D. Gladden in the 2010 inaugural draft (Round 22, Pick 17, 647th overall Pick). |
| Drafted RF T. Dowd in the 2010 inaugural draft (Round 23, Pick 14, 674th overall Pick). |
| Drafted RF D. Miller in the 2010 inaugural draft (Round 24, Pick 17, 707th overall Pick). |
| Drafted 3B B. Werber in the 2010 inaugural draft (Round 25, Pick 14, 734th overall Pick). |
| Drafted 2B B. Herman in the 2010 inaugural draft (Round 26, Pick 17, 767th overall Pick). |
| Drafted MR B. Mathews in the 2010 inaugural draft (Round 27, Pick 14, 794th overall Pick). |
| Drafted LF P. Cavarretta in the 2010 inaugural draft (Round 28, Pick 17, 827th overall Pick). |
| Drafted RF J. Ryan in the 2010 inaugural draft (Round 29, Pick 14, 854th overall Pick). |
| Drafted SP H. Brown in the 2010 inaugural draft (Round 30, Pick 17, 887th overall Pick). |
| Drafted 3B P. Whitney in the 2010 inaugural draft (Round 31, Pick 14, 914th overall Pick). |
| Drafted SP B. Walters in the 2010 inaugural draft (Round 32, Pick 17, 947th overall Pick). |
| Drafted 1B D. Alexander in the 2010 inaugural draft (Round 33, Pick 14, 974th overall Pick). |
| Drafted SS L. Lary in the 2010 inaugural draft (Round 34, Pick 17, 1007th overall Pick). |
| Drafted MR T. Adams in the 2010 inaugural draft (Round 35, Pick 14, 1034th overall Pick). |
| Drafted C J. Roseboro in the 2010 inaugural draft (Round 36, Pick 17, 1067th overall Pick). |
| Drafted 1B H. Walker in the 2010 inaugural draft (Round 37, Pick 14, 1094th overall Pick). |
| Drafted 1B H. Larkin in the 2010 inaugural draft (Round 38, Pick 17, 1127th overall Pick). |
| Drafted SP B. O'Brien in the 2010 inaugural draft (Round 39, Pick 14, 1154th overall Pick). |
| Drafted SS D. Pratt in the 2010 inaugural draft (Round 40, Pick 17, 1187th overall Pick). |
