| Friday, January 1st, 2010 |
| Drafted 1B L. Gehrig in the 2010 inaugural draft (Round 1, Pick 7, 7th overall Pick). |
| Drafted SS E. Delahanty in the 2010 inaugural draft (Round 2, Pick 24, 54th overall Pick). |
| Drafted RF J. Canseco in the 2010 inaugural draft (Round 3, Pick 7, 67th overall Pick). |
| Drafted SP A. Joss in the 2010 inaugural draft (Round 4, Pick 24, 114th overall Pick). |
| Drafted SP R. Nelson in the 2010 inaugural draft (Round 5, Pick 7, 127th overall Pick). |
| Drafted C G. Mancuso in the 2010 inaugural draft (Round 6, Pick 24, 174th overall Pick). |
| Drafted SP G. McQuillan in the 2010 inaugural draft (Round 7, Pick 7, 187th overall Pick). |
| Drafted 2B C. Gehringer in the 2010 inaugural draft (Round 8, Pick 24, 234th overall Pick). |
| Drafted CF H. Wilson in the 2010 inaugural draft (Round 9, Pick 7, 247th overall Pick). |
| Drafted LF R. Kiner in the 2010 inaugural draft (Round 10, Pick 24, 294th overall Pick). |
| Drafted MR R. Roberts in the 2010 inaugural draft (Round 11, Pick 7, 307th overall Pick). |
| Drafted MR A. McBean in the 2010 inaugural draft (Round 12, Pick 24, 354th overall Pick). |
| Drafted SP S. Coveleski in the 2010 inaugural draft (Round 13, Pick 7, 367th overall Pick). |
| Drafted MR R. Wolff in the 2010 inaugural draft (Round 14, Pick 24, 414th overall Pick). |
| Drafted SP J. Sambito in the 2010 inaugural draft (Round 15, Pick 7, 427th overall Pick). |
| Drafted 3B D. Holmes in the 2010 inaugural draft (Round 16, Pick 24, 474th overall Pick). |
| Drafted CL J. Kern in the 2010 inaugural draft (Round 17, Pick 7, 487th overall Pick). |
| Drafted C C. Fisk in the 2010 inaugural draft (Round 18, Pick 24, 534th overall Pick). |
| Drafted LF C. Hafey in the 2010 inaugural draft (Round 19, Pick 7, 547th overall Pick). |
| Drafted 1B M. Epstein in the 2010 inaugural draft (Round 20, Pick 24, 594th overall Pick). |
| Drafted SP R. Ames in the 2010 inaugural draft (Round 21, Pick 7, 607th overall Pick). |
| Drafted LF D. Kingman in the 2010 inaugural draft (Round 22, Pick 24, 654th overall Pick). |
| Drafted SP L. Warneke in the 2010 inaugural draft (Round 23, Pick 7, 667th overall Pick). |
| Drafted SP D. Roberts in the 2010 inaugural draft (Round 24, Pick 24, 714th overall Pick). |
| Drafted SP M. Caldwell in the 2010 inaugural draft (Round 25, Pick 7, 727th overall Pick). |
