| Friday, January 1st, 2010 |
| Drafted 3B J. Foxx in the 2010 inaugural draft (Round 1, Pick 13, 13th overall Pick). |
| Drafted 2B H. Trosky in the 2010 inaugural draft (Round 2, Pick 18, 48th overall Pick). |
| Drafted LF T. Conigliaro in the 2010 inaugural draft (Round 3, Pick 13, 73rd overall Pick). |
| Drafted SP H. Krause in the 2010 inaugural draft (Round 4, Pick 18, 108th overall Pick). |
| Drafted SP P. Werden in the 2010 inaugural draft (Round 5, Pick 13, 133rd overall Pick). |
| Drafted SS D. Force in the 2010 inaugural draft (Round 6, Pick 18, 168th overall Pick). |
| Drafted 1B H. Killebrew in the 2010 inaugural draft (Round 7, Pick 13, 193rd overall Pick). |
| Drafted SP D. Driscoll in the 2010 inaugural draft (Round 8, Pick 18, 228th overall Pick). |
| Drafted MR T. Niedenfuer in the 2010 inaugural draft (Round 9, Pick 13, 253rd overall Pick). |
| Drafted C T. Hundley in the 2010 inaugural draft (Round 10, Pick 18, 288th overall Pick). |
| Drafted RF R. Maris in the 2010 inaugural draft (Round 11, Pick 13, 313rd overall Pick). |
| Drafted SP N. Maddox in the 2010 inaugural draft (Round 12, Pick 18, 348th overall Pick). |
| Drafted MR H. Vaughn in the 2010 inaugural draft (Round 13, Pick 13, 373rd overall Pick). |
| Drafted CF L. Doby in the 2010 inaugural draft (Round 14, Pick 18, 408th overall Pick). |
| Drafted SP C. Mays in the 2010 inaugural draft (Round 15, Pick 13, 433rd overall Pick). |
| Drafted MR B. Lee in the 2010 inaugural draft (Round 16, Pick 18, 468th overall Pick). |
| Drafted MR S. Radinsky in the 2010 inaugural draft (Round 17, Pick 13, 493rd overall Pick). |
| Drafted C B. Freehan in the 2010 inaugural draft (Round 18, Pick 18, 528th overall Pick). |
| Drafted RF V. Wertz in the 2010 inaugural draft (Round 19, Pick 13, 553rd overall Pick). |
| Drafted LF D. Justice in the 2010 inaugural draft (Round 20, Pick 18, 588th overall Pick). |
| Drafted 2B C. Michaels in the 2010 inaugural draft (Round 21, Pick 13, 613rd overall Pick). |
| Drafted SP M. Stratton in the 2010 inaugural draft (Round 22, Pick 18, 648th overall Pick). |
| Drafted SP T. Bonham in the 2010 inaugural draft (Round 23, Pick 13, 673rd overall Pick). |
| Drafted SP L. Gomez in the 2010 inaugural draft (Round 24, Pick 18, 708th overall Pick). |
| Drafted SP B. Singer in the 2010 inaugural draft (Round 25, Pick 13, 733rd overall Pick). |
