| Friday, January 1st, 2010 |
| Drafted 1B B. Taylor in the 2010 inaugural draft (Round 1, Pick 19, 19th overall Pick). |
| Drafted 2B G. Scales in the 2010 inaugural draft (Round 2, Pick 12, 42nd overall Pick). |
| Drafted RF A. Kaline in the 2010 inaugural draft (Round 3, Pick 19, 79th overall Pick). |
| Drafted SP E. Morris in the 2010 inaugural draft (Round 4, Pick 12, 102nd overall Pick). |
| Drafted SP P. Conway in the 2010 inaugural draft (Round 5, Pick 19, 139th overall Pick). |
| Drafted SS O. Burns in the 2010 inaugural draft (Round 6, Pick 12, 162nd overall Pick). |
| Drafted SP R. Collins in the 2010 inaugural draft (Round 7, Pick 19, 199th overall Pick). |
| Drafted SP J. Lynch in the 2010 inaugural draft (Round 8, Pick 12, 222nd overall Pick). |
| Drafted CF D. Snider in the 2010 inaugural draft (Round 9, Pick 19, 259th overall Pick). |
| Drafted 3B R. Bresnahan in the 2010 inaugural draft (Round 10, Pick 12, 282nd overall Pick). |
| Drafted SP L. Dierker in the 2010 inaugural draft (Round 11, Pick 19, 319th overall Pick). |
| Drafted CL G. Olson in the 2010 inaugural draft (Round 12, Pick 12, 342nd overall Pick). |
| Drafted C G. Hartnett in the 2010 inaugural draft (Round 13, Pick 19, 379th overall Pick). |
| Drafted MR T. Hughson in the 2010 inaugural draft (Round 14, Pick 12, 402nd overall Pick). |
| Drafted MR T. Seaver in the 2010 inaugural draft (Round 15, Pick 19, 439th overall Pick). |
| Drafted MR O. Hershiser in the 2010 inaugural draft (Round 16, Pick 12, 462nd overall Pick). |
| Drafted LF D. Erstad in the 2010 inaugural draft (Round 17, Pick 19, 499th overall Pick). |
| Drafted C J. Romano in the 2010 inaugural draft (Round 18, Pick 12, 522nd overall Pick). |
| Drafted CF S. Chapman in the 2010 inaugural draft (Round 19, Pick 19, 559th overall Pick). |
| Drafted 1B A. Galarraga in the 2010 inaugural draft (Round 20, Pick 12, 582nd overall Pick). |
| Drafted 1B R. York in the 2010 inaugural draft (Round 21, Pick 19, 619th overall Pick). |
| Drafted RF D. Murphy in the 2010 inaugural draft (Round 22, Pick 12, 642nd overall Pick). |
| Drafted RF F. Jones in the 2010 inaugural draft (Round 23, Pick 19, 679th overall Pick). |
| Drafted 2B R. Youngs in the 2010 inaugural draft (Round 24, Pick 12, 702nd overall Pick). |
| Drafted 2B N. Fox in the 2010 inaugural draft (Round 25, Pick 19, 739th overall Pick). |
