| Friday, January 1st, 2010 |
| Drafted RF T. Williams in the 2010 inaugural draft (Round 1, Pick 2, 2nd overall Pick). |
| Drafted CF S. Musial in the 2010 inaugural draft (Round 2, Pick 29, 59th overall Pick). |
| Drafted SS E. Delahanty in the 2010 inaugural draft (Round 3, Pick 2, 62nd overall Pick). |
| Drafted SP E. Cicotte in the 2010 inaugural draft (Round 4, Pick 29, 119th overall Pick). |
| Drafted SP J. Williams in the 2010 inaugural draft (Round 5, Pick 2, 122nd overall Pick). |
| Drafted 2B J. Hodapp in the 2010 inaugural draft (Round 6, Pick 29, 179th overall Pick). |
| Drafted 1B J. Gentile in the 2010 inaugural draft (Round 7, Pick 2, 182nd overall Pick). |
| Drafted SP C. Radbourn in the 2010 inaugural draft (Round 8, Pick 29, 239th overall Pick). |
| Drafted C G. Hartnett in the 2010 inaugural draft (Round 9, Pick 2, 242nd overall Pick). |
| Drafted 3B F. Baker in the 2010 inaugural draft (Round 10, Pick 29, 299th overall Pick). |
| Drafted MR V. Romo in the 2010 inaugural draft (Round 11, Pick 2, 302nd overall Pick). |
| Drafted LF W. Covington in the 2010 inaugural draft (Round 12, Pick 29, 359th overall Pick). |
| Drafted SP R. Clemens in the 2010 inaugural draft (Round 13, Pick 2, 362nd overall Pick). |
| Drafted SP M. Drabowsky in the 2010 inaugural draft (Round 14, Pick 29, 419th overall Pick). |
| Drafted CL K. Tekulve in the 2010 inaugural draft (Round 15, Pick 2, 422nd overall Pick). |
| Drafted MR T. House in the 2010 inaugural draft (Round 16, Pick 29, 479th overall Pick). |
| Drafted MR G. Minton in the 2010 inaugural draft (Round 17, Pick 2, 482nd overall Pick). |
| Drafted C J. Bassler in the 2010 inaugural draft (Round 18, Pick 29, 539th overall Pick). |
| Drafted RF R. Maris in the 2010 inaugural draft (Round 19, Pick 2, 542nd overall Pick). |
| Drafted 1B R. York in the 2010 inaugural draft (Round 20, Pick 29, 599th overall Pick). |
| Drafted 1B M. Vaughn in the 2010 inaugural draft (Round 21, Pick 2, 602nd overall Pick). |
| Drafted RF J. Hickman in the 2010 inaugural draft (Round 22, Pick 29, 659th overall Pick). |
| Drafted SP T. McCarthy in the 2010 inaugural draft (Round 23, Pick 2, 662nd overall Pick). |
| Drafted SP K. Sanders in the 2010 inaugural draft (Round 24, Pick 29, 719th overall Pick). |
| Drafted SP N. Altrock in the 2010 inaugural draft (Round 25, Pick 2, 722nd overall Pick). |
