| Friday, January 1st, 2010 |
| Drafted SS A. Vaughan in the 2010 inaugural draft (Round 1, Pick 10, 10th overall Pick). |
| Drafted LF B. Herman in the 2010 inaugural draft (Round 2, Pick 21, 51st overall Pick). |
| Drafted 3B D. Allen in the 2010 inaugural draft (Round 3, Pick 10, 70th overall Pick). |
| Drafted SP A. Joss in the 2010 inaugural draft (Round 4, Pick 21, 111st overall Pick). |
| Drafted SP H. Camnitz in the 2010 inaugural draft (Round 5, Pick 10, 130th overall Pick). |
| Drafted 2B T. Lazzeri in the 2010 inaugural draft (Round 6, Pick 21, 171st overall Pick). |
| Drafted CL J. Wood in the 2010 inaugural draft (Round 7, Pick 10, 190th overall Pick). |
| Drafted SP D. Driscoll in the 2010 inaugural draft (Round 8, Pick 21, 231st overall Pick). |
| Drafted CF E. Averill in the 2010 inaugural draft (Round 9, Pick 10, 250th overall Pick). |
| Drafted C Y. Berra in the 2010 inaugural draft (Round 10, Pick 21, 291st overall Pick). |
| Drafted SP F. Owen in the 2010 inaugural draft (Round 11, Pick 10, 310th overall Pick). |
| Drafted CL G. Olson in the 2010 inaugural draft (Round 12, Pick 21, 351st overall Pick). |
| Drafted SP M. Cooper in the 2010 inaugural draft (Round 13, Pick 10, 370th overall Pick). |
| Drafted 1B R. Palmeiro in the 2010 inaugural draft (Round 14, Pick 21, 411st overall Pick). |
| Drafted RF G. Selkirk in the 2010 inaugural draft (Round 15, Pick 10, 430th overall Pick). |
| Drafted MR O. Hershiser in the 2010 inaugural draft (Round 16, Pick 21, 471st overall Pick). |
| Drafted MR J. Key in the 2010 inaugural draft (Round 17, Pick 10, 490th overall Pick). |
| Drafted MR S. Perry in the 2010 inaugural draft (Round 18, Pick 21, 531st overall Pick). |
| Drafted C S. Sutcliffe in the 2010 inaugural draft (Round 19, Pick 10, 550th overall Pick). |
| Drafted 1B J. Mayberry in the 2010 inaugural draft (Round 20, Pick 21, 591st overall Pick). |
| Drafted RF J. Heath in the 2010 inaugural draft (Round 21, Pick 10, 610th overall Pick). |
| Drafted SP A. Hammaker in the 2010 inaugural draft (Round 22, Pick 21, 651st overall Pick). |
| Drafted SP E. Blackwell in the 2010 inaugural draft (Round 23, Pick 10, 670th overall Pick). |
| Drafted SP A. Orth in the 2010 inaugural draft (Round 24, Pick 21, 711st overall Pick). |
| Drafted SP M. Lolich in the 2010 inaugural draft (Round 25, Pick 10, 730th overall Pick). |
