| Friday, January 1st, 2010 |
| Drafted C M. Piazza in the 2010 inaugural draft (Round 1, Pick 25, 25th overall Pick). |
| Drafted RF H. Aaron in the 2010 inaugural draft (Round 2, Pick 6, 36th overall Pick). |
| Drafted CF F. Lynn in the 2010 inaugural draft (Round 3, Pick 25, 85th overall Pick). |
| Drafted SP T. McGraw in the 2010 inaugural draft (Round 4, Pick 6, 96th overall Pick). |
| Drafted SP B. Harvey in the 2010 inaugural draft (Round 5, Pick 25, 145th overall Pick). |
| Drafted 3B B. Joyce in the 2010 inaugural draft (Round 6, Pick 6, 156th overall Pick). |
| Drafted SP F. Goldsmith in the 2010 inaugural draft (Round 7, Pick 25, 205th overall Pick). |
| Drafted 1B E. Martinez in the 2010 inaugural draft (Round 8, Pick 6, 216th overall Pick). |
| Drafted MR J. Brewer in the 2010 inaugural draft (Round 9, Pick 25, 265th overall Pick). |
| Drafted LF T. Francona in the 2010 inaugural draft (Round 10, Pick 6, 276th overall Pick). |
| Drafted MR J. Scott in the 2010 inaugural draft (Round 11, Pick 25, 325th overall Pick). |
| Drafted MR B. Knepper in the 2010 inaugural draft (Round 12, Pick 6, 336th overall Pick). |
| Drafted 2B J. Dykes in the 2010 inaugural draft (Round 13, Pick 25, 385th overall Pick). |
| Drafted MR R. Wolff in the 2010 inaugural draft (Round 14, Pick 6, 396th overall Pick). |
| Drafted SS H. Brooks in the 2010 inaugural draft (Round 15, Pick 25, 445th overall Pick). |
| Drafted SP B. Grimes in the 2010 inaugural draft (Round 16, Pick 6, 456th overall Pick). |
| Drafted SP D. Brown in the 2010 inaugural draft (Round 17, Pick 25, 505th overall Pick). |
| Drafted C D. Dietz in the 2010 inaugural draft (Round 18, Pick 6, 516th overall Pick). |
| Drafted RF C. Yastrzemski in the 2010 inaugural draft (Round 19, Pick 25, 565th overall Pick). |
| Drafted LF P. O'Neill in the 2010 inaugural draft (Round 20, Pick 6, 576th overall Pick). |
| Drafted 1B R. Collins in the 2010 inaugural draft (Round 21, Pick 25, 625th overall Pick). |
| Drafted 1B W. Dropo in the 2010 inaugural draft (Round 22, Pick 6, 636th overall Pick). |
| Drafted LF A. Pafko in the 2010 inaugural draft (Round 23, Pick 25, 685th overall Pick). |
| Drafted SS V. Castilla in the 2010 inaugural draft (Round 24, Pick 6, 696th overall Pick). |
| Drafted SP T. Higuera in the 2010 inaugural draft (Round 25, Pick 25, 745th overall Pick). |
