| Friday, January 1st, 2010 |
| Drafted 3B L. Meyerle in the 2010 inaugural draft (Round 1, Pick 28, 28th overall Pick). |
| Drafted CF C. Cedeno in the 2010 inaugural draft (Round 2, Pick 3, 33rd overall Pick). |
| Drafted LF J. Medwick in the 2010 inaugural draft (Round 3, Pick 28, 88th overall Pick). |
| Drafted SP B. Henry in the 2010 inaugural draft (Round 4, Pick 3, 93rd overall Pick). |
| Drafted SP D. Rudolph in the 2010 inaugural draft (Round 5, Pick 28, 148th overall Pick). |
| Drafted 1B J. Doyle in the 2010 inaugural draft (Round 6, Pick 3, 153rd overall Pick). |
| Drafted SP D. Chance in the 2010 inaugural draft (Round 7, Pick 28, 208th overall Pick). |
| Drafted SP A. Hrabosky in the 2010 inaugural draft (Round 8, Pick 3, 213rd overall Pick). |
| Drafted SP H. Smith in the 2010 inaugural draft (Round 9, Pick 28, 268th overall Pick). |
| Drafted RF W. Keeler in the 2010 inaugural draft (Round 10, Pick 3, 273rd overall Pick). |
| Drafted C J. Blanchard in the 2010 inaugural draft (Round 11, Pick 28, 328th overall Pick). |
| Drafted 2B L. Bierbauer in the 2010 inaugural draft (Round 12, Pick 3, 333rd overall Pick). |
| Drafted CL W. Wyatt in the 2010 inaugural draft (Round 13, Pick 28, 388th overall Pick). |
| Drafted SS E. McKean in the 2010 inaugural draft (Round 14, Pick 3, 393rd overall Pick). |
| Drafted CL J. Kern in the 2010 inaugural draft (Round 15, Pick 28, 448th overall Pick). |
| Drafted MR D. Redding in the 2010 inaugural draft (Round 16, Pick 3, 453rd overall Pick). |
| Drafted MR D. Baldwin in the 2010 inaugural draft (Round 17, Pick 28, 508th overall Pick). |
| Drafted C F. Chance in the 2010 inaugural draft (Round 18, Pick 3, 513rd overall Pick). |
| Drafted MR M. Queen in the 2010 inaugural draft (Round 19, Pick 28, 568th overall Pick). |
| Drafted LF K. Williams in the 2010 inaugural draft (Round 20, Pick 3, 573rd overall Pick). |
| Drafted LF G. Stone in the 2010 inaugural draft (Round 21, Pick 28, 628th overall Pick). |
| Drafted CF W. Moses in the 2010 inaugural draft (Round 22, Pick 3, 633rd overall Pick). |
| Drafted SS K. Elberfeld in the 2010 inaugural draft (Round 23, Pick 28, 688th overall Pick). |
| Drafted SS B. Larkin in the 2010 inaugural draft (Round 24, Pick 3, 693rd overall Pick). |
| Drafted RF K. Griffey, Sr. in the 2010 inaugural draft (Round 25, Pick 28, 748th overall Pick). |
