| Friday, January 1st, 2010 |
| Drafted SS A. Vaughan in the 2010 inaugural draft (Round 1, Pick 11, 11th overall Pick). |
| Drafted CF B. Higginson in the 2010 inaugural draft (Round 2, Pick 20, 50th overall Pick). |
| Drafted C J. Bench in the 2010 inaugural draft (Round 3, Pick 11, 71st overall Pick). |
| Drafted SP H. Krause in the 2010 inaugural draft (Round 4, Pick 20, 110th overall Pick). |
| Drafted SP E. Seward in the 2010 inaugural draft (Round 5, Pick 11, 131st overall Pick). |
| Drafted 1B H. Killebrew in the 2010 inaugural draft (Round 6, Pick 20, 170th overall Pick). |
| Drafted SP D. Chance in the 2010 inaugural draft (Round 7, Pick 11, 191st overall Pick). |
| Drafted 2B F. Lindstrom in the 2010 inaugural draft (Round 8, Pick 20, 230th overall Pick). |
| Drafted MR R. Guidry in the 2010 inaugural draft (Round 9, Pick 11, 251st overall Pick). |
| Drafted RF J. Gonzalez in the 2010 inaugural draft (Round 10, Pick 20, 290th overall Pick). |
| Drafted LF C. Keller in the 2010 inaugural draft (Round 11, Pick 11, 311st overall Pick). |
| Drafted SP E. Shore in the 2010 inaugural draft (Round 12, Pick 20, 350th overall Pick). |
| Drafted SP C. Radbourn in the 2010 inaugural draft (Round 13, Pick 11, 371st overall Pick). |
| Drafted MR M. Cuellar in the 2010 inaugural draft (Round 14, Pick 20, 410th overall Pick). |
| Drafted 3B C. Ripken, Jr. in the 2010 inaugural draft (Round 15, Pick 11, 431st overall Pick). |
| Drafted CL R. Eastwick in the 2010 inaugural draft (Round 16, Pick 20, 470th overall Pick). |
| Drafted MR T. House in the 2010 inaugural draft (Round 17, Pick 11, 491st overall Pick). |
| Drafted C B. Freehan in the 2010 inaugural draft (Round 18, Pick 20, 530th overall Pick). |
| Drafted RF D. Ennis in the 2010 inaugural draft (Round 19, Pick 11, 551st overall Pick). |
| Drafted LF C. Lee in the 2010 inaugural draft (Round 20, Pick 20, 590th overall Pick). |
| Drafted LF D. Justice in the 2010 inaugural draft (Round 21, Pick 11, 611st overall Pick). |
| Drafted RF J. Hickman in the 2010 inaugural draft (Round 22, Pick 20, 650th overall Pick). |
| Drafted 3B B. Robinson in the 2010 inaugural draft (Round 23, Pick 11, 671st overall Pick). |
| Drafted 2B J. Gordon in the 2010 inaugural draft (Round 24, Pick 20, 710th overall Pick). |
| Drafted 2B N. Fox in the 2010 inaugural draft (Round 25, Pick 11, 731st overall Pick). |
| Drafted RF I. Boone in the 2010 inaugural draft (Round 26, Pick 20, 770th overall Pick). |
| Drafted MR E. Fisher in the 2010 inaugural draft (Round 27, Pick 11, 791st overall Pick). |
| Drafted LF J. Barrett in the 2010 inaugural draft (Round 28, Pick 20, 830th overall Pick). |
| Drafted 2B B. Boone in the 2010 inaugural draft (Round 29, Pick 11, 851st overall Pick). |
| Drafted SS D. Decinces in the 2010 inaugural draft (Round 30, Pick 20, 890th overall Pick). |
| Drafted CF J. Northrup in the 2010 inaugural draft (Round 31, Pick 11, 911st overall Pick). |
| Drafted CL L. Leifield in the 2010 inaugural draft (Round 32, Pick 20, 950th overall Pick). |
| Drafted C D. Crandall in the 2010 inaugural draft (Round 33, Pick 11, 971st overall Pick). |
| Drafted MR W. Moore in the 2010 inaugural draft (Round 34, Pick 20, 1010th overall Pick). |
| Drafted SP G. Mullin in the 2010 inaugural draft (Round 35, Pick 11, 1031st overall Pick). |
| Drafted 3B G. Nettles in the 2010 inaugural draft (Round 36, Pick 20, 1070th overall Pick). |
| Drafted 1B E. Kranepool in the 2010 inaugural draft (Round 37, Pick 11, 1091st overall Pick). |
| Drafted CL H. Woodeshick in the 2010 inaugural draft (Round 38, Pick 20, 1130th overall Pick). |
| Drafted MR S. Smith in the 2010 inaugural draft (Round 39, Pick 11, 1151st overall Pick). |
| Drafted SS T. Foli in the 2010 inaugural draft (Round 40, Pick 20, 1190th overall Pick). |
| Drafted LF C. Milan in the 2010 inaugural draft (Round 41, Pick 11, 1211st overall Pick). |
