| Friday, January 1st, 2010 |
| Drafted SS H. Duffy in the 2010 inaugural draft (Round 1, Pick 16, 16th overall Pick). |
| Drafted 1B G. Sisler in the 2010 inaugural draft (Round 2, Pick 15, 45th overall Pick). |
| Drafted LF J. Medwick in the 2010 inaugural draft (Round 3, Pick 16, 76th overall Pick). |
| Drafted SP C. Mathewson in the 2010 inaugural draft (Round 4, Pick 15, 105th overall Pick). |
| Drafted SP J. McGinnity in the 2010 inaugural draft (Round 5, Pick 16, 136th overall Pick). |
| Drafted 3B B. Bradley in the 2010 inaugural draft (Round 6, Pick 15, 165th overall Pick). |
| Drafted SP G. Maddux in the 2010 inaugural draft (Round 7, Pick 16, 196th overall Pick). |
| Drafted SP A. Hrabosky in the 2010 inaugural draft (Round 8, Pick 15, 225th overall Pick). |
| Drafted 2B J. Robinson in the 2010 inaugural draft (Round 9, Pick 16, 256th overall Pick). |
| Drafted MR W. Mitchell in the 2010 inaugural draft (Round 10, Pick 15, 285th overall Pick). |
| Drafted C J. Blanchard in the 2010 inaugural draft (Round 11, Pick 16, 316th overall Pick). |
| Drafted RF G. Goslin in the 2010 inaugural draft (Round 12, Pick 15, 345th overall Pick). |
| Drafted CF E. Averill in the 2010 inaugural draft (Round 13, Pick 16, 376th overall Pick). |
| Drafted MR R. Wolff in the 2010 inaugural draft (Round 14, Pick 15, 405th overall Pick). |
| Drafted MR L. McDaniel in the 2010 inaugural draft (Round 15, Pick 16, 436th overall Pick). |
| Drafted SP S. Bahnsen in the 2010 inaugural draft (Round 16, Pick 15, 465th overall Pick). |
| Drafted CL J. Kern in the 2010 inaugural draft (Round 17, Pick 16, 496th overall Pick). |
| Drafted C B. Phelps in the 2010 inaugural draft (Round 18, Pick 15, 525th overall Pick). |
| Drafted DH R. Jefferson in the 2010 inaugural draft (Round 19, Pick 16, 556th overall Pick). |
| Drafted SP A. Spalding in the 2010 inaugural draft (Round 20, Pick 15, 585th overall Pick). |
| Drafted 1B J. Bottomley in the 2010 inaugural draft (Round 21, Pick 16, 616th overall Pick). |
| Drafted 3B J. Torre in the 2010 inaugural draft (Round 22, Pick 15, 645th overall Pick). |
| Drafted SP J. Beazley in the 2010 inaugural draft (Round 23, Pick 16, 676th overall Pick). |
| Drafted SP F. Jenkins in the 2010 inaugural draft (Round 24, Pick 15, 705th overall Pick). |
| Drafted SP L. Smith in the 2010 inaugural draft (Round 25, Pick 16, 736th overall Pick). |
| Drafted SP J. Powell in the 2010 inaugural draft (Round 26, Pick 15, 765th overall Pick). |
| Drafted CF J. Frederick in the 2010 inaugural draft (Round 27, Pick 16, 796th overall Pick). |
| Drafted 3B T. Fryman in the 2010 inaugural draft (Round 28, Pick 15, 825th overall Pick). |
| Drafted 2B J. Bell in the 2010 inaugural draft (Round 29, Pick 16, 856th overall Pick). |
| Drafted LF J. O'Rourke in the 2010 inaugural draft (Round 30, Pick 15, 885th overall Pick). |
| Drafted RF D. White in the 2010 inaugural draft (Round 31, Pick 16, 916th overall Pick). |
| Drafted SP R. Reuschel in the 2010 inaugural draft (Round 32, Pick 15, 945th overall Pick). |
| Drafted C M. Sanguillen in the 2010 inaugural draft (Round 33, Pick 16, 976th overall Pick). |
| Drafted MR S. Fernandez in the 2010 inaugural draft (Round 34, Pick 15, 1005th overall Pick). |
| Drafted SP D. Luque in the 2010 inaugural draft (Round 35, Pick 16, 1036th overall Pick). |
| Drafted 1B C. Cooper in the 2010 inaugural draft (Round 36, Pick 15, 1065th overall Pick). |
| Drafted SS M. Wills in the 2010 inaugural draft (Round 37, Pick 16, 1096th overall Pick). |
| Drafted MR A. Holland in the 2010 inaugural draft (Round 38, Pick 15, 1125th overall Pick). |
| Drafted CL M. Jackson in the 2010 inaugural draft (Round 39, Pick 16, 1156th overall Pick). |
| Drafted 1B G. Burns in the 2010 inaugural draft (Round 40, Pick 15, 1185th overall Pick). |
