| Friday, January 1st, 2010 |
| Drafted 3B J. Foxx in the 2010 inaugural draft (Round 1, Pick 12, 12th overall Pick). |
| Drafted SS J. Wilson in the 2010 inaugural draft (Round 2, Pick 19, 49th overall Pick). |
| Drafted RF A. Kaline in the 2010 inaugural draft (Round 3, Pick 12, 72nd overall Pick). |
| Drafted SP R. Waddell in the 2010 inaugural draft (Round 4, Pick 19, 109th overall Pick). |
| Drafted SP C. Bender in the 2010 inaugural draft (Round 5, Pick 12, 132nd overall Pick). |
| Drafted MR B. Blyleven in the 2010 inaugural draft (Round 6, Pick 19, 169th overall Pick). |
| Drafted SP G. McQuillan in the 2010 inaugural draft (Round 7, Pick 12, 192nd overall Pick). |
| Drafted C B. Dickey in the 2010 inaugural draft (Round 8, Pick 19, 229th overall Pick). |
| Drafted CF H. Wilson in the 2010 inaugural draft (Round 9, Pick 12, 252nd overall Pick). |
| Drafted 2B L. Doyle in the 2010 inaugural draft (Round 10, Pick 19, 289th overall Pick). |
| Drafted MR M. Stottlemyre in the 2010 inaugural draft (Round 11, Pick 12, 312nd overall Pick). |
| Drafted CL G. Olson in the 2010 inaugural draft (Round 12, Pick 19, 349th overall Pick). |
| Drafted MR P. Ragan in the 2010 inaugural draft (Round 13, Pick 12, 372nd overall Pick). |
| Drafted SP R. Narleski in the 2010 inaugural draft (Round 14, Pick 19, 409th overall Pick). |
| Drafted 1B J. Fournier in the 2010 inaugural draft (Round 15, Pick 12, 432nd overall Pick). |
| Drafted SP E. Shore in the 2010 inaugural draft (Round 16, Pick 19, 469th overall Pick). |
| Drafted LF D. Erstad in the 2010 inaugural draft (Round 17, Pick 12, 492nd overall Pick). |
| Drafted C J. Grim in the 2010 inaugural draft (Round 18, Pick 19, 529th overall Pick). |
| Drafted RF S. Lezcano in the 2010 inaugural draft (Round 19, Pick 12, 552nd overall Pick). |
| Drafted 1B E. Swartwood in the 2010 inaugural draft (Round 20, Pick 19, 589th overall Pick). |
| Drafted 1B C. McVey in the 2010 inaugural draft (Round 21, Pick 12, 612nd overall Pick). |
| Drafted SS T. Daly in the 2010 inaugural draft (Round 22, Pick 19, 649th overall Pick). |
| Drafted SP D. McLain in the 2010 inaugural draft (Round 23, Pick 12, 672nd overall Pick). |
| Drafted SP D. Roberts in the 2010 inaugural draft (Round 24, Pick 19, 709th overall Pick). |
| Drafted SP W. McDonald in the 2010 inaugural draft (Round 25, Pick 12, 732nd overall Pick). |
