| Friday, January 1st, 2010 |
| Drafted CF C. Cedeno in the 2010 inaugural draft (Round 1, Pick 30, 30th overall Pick). |
| Drafted 2B G. Scales in the 2010 inaugural draft (Round 2, Pick 1, 31st overall Pick). |
| Drafted 3B B. Bradley in the 2010 inaugural draft (Round 3, Pick 30, 90th overall Pick). |
| Drafted SP E. Walsh in the 2010 inaugural draft (Round 4, Pick 1, 91st overall Pick). |
| Drafted SP S. King in the 2010 inaugural draft (Round 5, Pick 30, 150th overall Pick). |
| Drafted SS J. Sewell in the 2010 inaugural draft (Round 6, Pick 1, 151st overall Pick). |
| Drafted SP S. Rogers in the 2010 inaugural draft (Round 7, Pick 30, 210th overall Pick). |
| Drafted CL D. Eckersley in the 2010 inaugural draft (Round 8, Pick 1, 211st overall Pick). |
| Drafted 1B H. Heilmann in the 2010 inaugural draft (Round 9, Pick 30, 270th overall Pick). |
| Drafted C S. Hogan in the 2010 inaugural draft (Round 10, Pick 1, 271st overall Pick). |
| Drafted LF T. Francona in the 2010 inaugural draft (Round 11, Pick 30, 330th overall Pick). |
| Drafted MR H. Newhouser in the 2010 inaugural draft (Round 12, Pick 1, 331st overall Pick). |
| Drafted RF L. O'Doul in the 2010 inaugural draft (Round 13, Pick 30, 390th overall Pick). |
| Drafted MR R. Patterson in the 2010 inaugural draft (Round 14, Pick 1, 391st overall Pick). |
| Drafted MR W. Ford in the 2010 inaugural draft (Round 15, Pick 30, 450th overall Pick). |
| Drafted SP F. Valenzuela in the 2010 inaugural draft (Round 16, Pick 1, 451st overall Pick). |
| Drafted SP W. Dismukes in the 2010 inaugural draft (Round 17, Pick 30, 510th overall Pick). |
| Drafted C T. Hundley in the 2010 inaugural draft (Round 18, Pick 1, 511st overall Pick). |
| Drafted RF J. Cassidy in the 2010 inaugural draft (Round 19, Pick 30, 570th overall Pick). |
| Drafted RF G. Selkirk in the 2010 inaugural draft (Round 20, Pick 1, 571st overall Pick). |
| Drafted RF T. Holmes in the 2010 inaugural draft (Round 21, Pick 30, 630th overall Pick). |
| Drafted LF B. Paschal in the 2010 inaugural draft (Round 22, Pick 1, 631st overall Pick). |
| Drafted SP L. Cadore in the 2010 inaugural draft (Round 23, Pick 30, 690th overall Pick). |
| Drafted SP B. Byrd in the 2010 inaugural draft (Round 24, Pick 1, 691st overall Pick). |
| Drafted SP J. Koosman in the 2010 inaugural draft (Round 25, Pick 30, 750th overall Pick). |
